Retrotransposons are mutagenic units able to move within the genome. Despite many
defenses deployed by the host to suppress potentially harmful activities of retrotransposons …

Transposable elements (TEs) are constitutive components of both eukaryotic and
prokaryotic genomes. The role of TEs in the evolution of genes and genomes has been …

Promoters are structurally and functionally diverse gene regulatory regions. The presence or
absence of sequence motifs and the spacing between the motifs defines the properties of …

Many epidemiological observational studies suggest that a high-fat diet (HFD) accelerates
the risk of colorectal cancer (CRC). Inflammation can play a key role in the relationship …

One of the main functions of the piwi‐interacting RNA pathway is the post‐transcriptional
silencing of transposable elements in the germline of many species. In insects, proteins …

Background Chromatin architecture is critical for gene expression during development.
Matrix attachment regions (MARs) control and regulate chromatin dynamics. The position of …

Transposable elements (TEs) are not randomly distributed in the genome. A genome-wide
analysis of the D. melanogaster genome found that differences in TE density across 50 kb …

The nuclear matrix (NM), or nuclear skeleton, is the non-chromatin, ribonucleoproteinaceous
framework that is resistant to high ionic strength buffers, nonionic detergents, and nucleolytic …

Where possible, developments enabling the establishment of cell lines with predictable,
long-term stable expression capacity are based on single-copy integrations at safe genomic …

The study of nuclear matrix (NuMat) over the last 40 years has been limited to either isolated
nuclei from tissues or cells grown in culture. Here, we provide a protocol for NuMat …