A perfect genome annotation is within reach with the proteomics and genomics alliance

J Armengaud - Current opinion in microbiology, 2009 - Elsevier
High-throughput identification of proteins and their accurate partial sequencing by shotgun
nanoLC-MS/MS are now feasible for any cellular model at a full genomic scale …

Targeted large‐scale analysis of protein acetylation

N Mischerikow, AJR Heck - Proteomics, 2011 - Wiley Online Library
Protein modifications are biologically important events that may be studied by mass
spectrometry‐based high‐throughput proteome analyses. In recent years, several new …

N-Terminal-oriented proteogenomics of the marine bacterium roseobacter denitrificans Och114 using N-Succinimidyloxycarbonylmethyl) tris (2, 4, 6-trimethoxyphenyl) …

C Bland, EM Hartmann, JA Christie-Oleza… - Molecular & Cellular …, 2014 - ASBMB
Given the ease of whole genome sequencing with next-generation sequencers, structural
and functional gene annotation is now purely based on automated prediction. However …

Magnetic immunoaffinity enrichment for selective capture and MS/MS analysis of N-terminal-TMPP-labeled peptides

C Bland, L Bellanger, J Armengaud - Journal of proteome …, 2014 - ACS Publications
Proteogenomics is the alliance of proteomics and genomics with the aim of better annotating
structural genes based on experimental, protein-based data items established by tandem …

Identification and sequencing of N-terminal peptides in proteins by LC-fluorescence-MS/MS: An approach to replacement of the Edman degradation

MM Vecchi, Y Xiao, D Wen - Analytical chemistry, 2019 - ACS Publications
Automated Edman degradation for sequencing is the classic tool for determining the N-
terminal sequences of proteins. Although it has been complemented or largely replaced by a …

Streamlining bottom-up protein identification based on selective ultraviolet photodissociation (UVPD) of chromophore-tagged histidine-and tyrosine-containing …

JR Aponte, L Vasicek, J Swaminathan, H Xu… - Analytical …, 2014 - ACS Publications
We report a fast and highly efficient diazonium reaction that couples a nitroazobenzene
chromophore to tyrosine and histidine residues, thus endowing peptides with high …

Dipeptidyl peptidase 9 (DPP9) from bovine testes: Identification and characterization as the short form by mass spectrometry

V Dubois, AM Lambeir, S Vandamme… - … et Biophysica Acta (BBA …, 2010 - Elsevier
The dipeptidyl peptidases (DPP) 8 and 9 belong to the DPP4 activity and/or structure
homologues (DASH). Recently, a DPP9-like protein was purified from bovine testes. The aim …

C-terminal de novo sequencing of peptides using oxazolone-based derivatization with bromine signature

JS Kim, M Shin, JS Song, S An, HJ Kim - Analytical biochemistry, 2011 - Elsevier
Due to almost identical chemical properties of C-terminal and side-chain carboxylic groups,
selective C-terminal derivatization has been difficult. Although oxazolone-based C-terminal …

A method for N-terminal de novo sequencing of N α-blocked proteins by mass spectrometry

C Nakajima, H Kuyama, T Nakazawa, O Nishimura… - Analyst, 2011 - pubs.rsc.org
A method for de novo sequencing of Nα-blocked proteins by mass spectrometry (MS) is
presented. The approach consists of enzymatic digestion of Nα-blocked protein, recovery of …

C-Terminal sequencing of protein by MALDI mass spectrometry through the specific derivatization of the α-carboxyl group with 3-aminopropyltris-(2, 4, 6 …

C Nakajima, H Kuyama, T Nakazawa… - Analytical and …, 2012 - Springer
We present here an approach to C-terminal sequencing of proteins by the procedure
consisting of the following:(1) derivatization of the C-terminal α-carboxyl group with 3 …