Human papilloma virus related squamous cell carcinomas of the head and neck: diagnosis, clinical implications and detection of HPV

EC Paver, AM Currie, R Gupta, JE Dahlstrom - Pathology, 2020 - Elsevier
High-risk human papillomavirus (HPV) positive squamous cell carcinoma (SCC) of the head
and neck is reported most commonly in the oropharynx but can also uncommonly be found …

Head and neck squamous cell carcinoma: risk factors, molecular alterations, immunology and peptide vaccines

Z Sun, X Sun, Z Chen, J Du, Y Wu - International Journal of Peptide …, 2022 - Springer
Head and neck squamous cell carcinoma (HNSCC) arises from the epithelial lining of the
oral cavity, hypopharynx, oropharynx, and larynx. There are several potential risk factors that …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

Human papillomavirus in oropharyngeal cancer: The changing face of a disease

J Mallen-St Clair, M Alani, MB Wang… - Biochimica et Biophysica …, 2016 - Elsevier
The last decade has brought about an unexpected rise in oropharyngeal squamous cell
carcinoma (OPSCC) primarily in white males from the ages of 40–55 years, with limited …

Oropharyngeal squamous cell carcinoma with discordant p16 and HPV mRNA results: incidence and characterization in a large, contemporary United States cohort

JR Shinn, SJ Davis, KA Lang-Kuhs… - The American journal …, 2021 - journals.lww.com
Early studies estimate that 5% to 10% of oropharyngeal squamous cell carcinomas
overexpress p16 but are unassociated with transcriptionally-active high-risk human …

The pathology of HPV-related head and neck cancer: implications for the diagnostic pathologist

WH Westra - Seminars in diagnostic pathology, 2015 - Elsevier
A subset of head and neck squamous cell carcinomas are caused by the human
papillomavirus (HPV). This HPV-related form of head and neck squamous cell carcinoma …

Histologic typing in oropharyngeal squamous cell carcinoma: a 4-year prospective practice study with p16 and high-risk HPV mRNA testing correlation

DD Gondim, W Haynes, X Wang… - The American journal …, 2016 - journals.lww.com
Oropharyngeal squamous cell carcinomas (OPSCCs) associated with human
papillomavirus (HPV) represent a distinct clinical and pathologic entity. The majority of HPV …

Parathyroid hormone-related protein serves as a prognostic indicator in oral squamous cell carcinoma

Z Lv, X Wu, W Cao, ZZ Shen, L Wang, FR Xie… - Journal of Experimental …, 2014 - Springer
Background In our previous study, parathyroid hormone-like hormone (PTHLH) which
encodes parathyroid hormone-related protein (PTHrP) was revealed to be up-regulated in …

Correlation of p16 immunohistochemistry in FNA biopsies with corresponding tissue specimens in HPV‐related squamous cell carcinomas of the oropharynx

JB Jalaly, JS Lewis Jr, BT Collins, X Wu… - Cancer …, 2015 - Wiley Online Library
BACKGROUND Human papillomavirus (HPV)‐related oropharyngeal squamous cell
carcinoma (SCC) is a unique form of carcinoma that is important to identify for prognosis and …

Oropharyngeal squamous cell carcinoma in 390 patients: analysis of clinical and histological criteria which significantly impact outcome

LDR Thompson, R Burchette, S Iganej… - Head and Neck …, 2020 - Springer
This study evaluates the prognostic impact of several factors in oropharyngeal squamous
cell carcinoma (OPSCC), controlling for human papillomavirus (HPV)-associated tumors and …