Executive summary Liver disease in the UK stands out as the one glaring exception to the
vast improvements made during the past 30 years in health and life expectancy for chronic …

BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis
in chronic liver disease; however, it is invasive, with the potential for serious complications …

Background & Aims The development of non-invasive liver fibrosis tests may enable earlier
identification of patients with non-alcoholic fatty liver disease (NAFLD) requiring referral to …

These updated guidelines on the management of abnormal liver blood tests have been
commissioned by the Clinical Services and Standards Committee (CSSC) of the British …

Background Phthalates have been largely used for years in varieties of products worldwide.
However, research on the joint toxic effect of various phthalates exposure on the liver is …

Background & Aims Current screening strategies for chronic liver disease focus on detection
of subclinical advanced liver fibrosis but cannot identify those at high future risk of severe …

Objectives To assess the feasibility of a novel diagnostic algorithm targeting patients with
risk factors for chronic liver disease in a community setting. Design Prospective cross …

Patients with chronic liver disease are often diagnosed during an index presentation to
hospital with decompensated cirrhosis or liver-related events, and these presentations are …

Background & Aims Liver function tests (LFTs) are frequently requested blood tests which
may indicate liver disease. LFTs are commonly abnormal, the causes of which can be …

The aspartate‐to‐alanine aminotransferase ratio (AAR) is associated with liver fibrosis, but
its predictive performance is suboptimal. We hypothesized that the association between …