The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Global consensus on the management of limbal stem cell deficiency

SX Deng, F Kruse, JAP Gomes, CC Chan, S Daya… - Cornea, 2020 - journals.lww.com
Purpose: In recent decades, the medical and surgical treatment of limbal stem cell deficiency
(LSCD) has evolved significantly through the incorporation of innovative pharmacological …

Topical losartan: practical guidance for clinical trials in the prevention and treatment of corneal scarring fibrosis and other eye diseases and disorders

SE Wilson - Journal of Ocular Pharmacology and Therapeutics, 2023 - liebertpub.com
Losartan is an angiotensin II receptor blocker (ARB) that impedes transforming growth factor
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …

[HTML][HTML] Diabetic corneal neuropathy

H Mansoor, HC Tan, MTY Lin, JS Mehta… - Journal of clinical …, 2020 - mdpi.com
Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …

Neurotrophic keratopathy: current challenges and future prospects

E NaPier, M Camacho, TF McDevitt… - Annals of …, 2022 - Taylor & Francis
Neurotrophic keratopathy (NK), or neurotrophic keratitis, is a degenerative condition that
results from decreased innervation to the cornea. The cornea is innervated by the …

[HTML][HTML] Treatment of non-infectious corneal injury: review of diagnostic agents, therapeutic medications, and future targets

DH Dang, KM Riaz, D Karamichos - Drugs, 2022 - Springer
Corneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic,
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …

[HTML][HTML] Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions

L Latta, FC Figueiredo, R Ashery-Padan, JM Collinson… - The ocular …, 2021 - Elsevier
Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

Alternative therapies for dry eye disease

R Mittal, S Patel, A Galor - Current opinion in ophthalmology, 2021 - journals.lww.com
Alternative therapies for dry eye disease : Current Opinion in Ophthalmology Alternative
therapies for dry eye disease : Current Opinion in Ophthalmology Log in or Register Subscribe …

Comparison of the efficacy of topical insulin with autologous serum eye drops in persistent epithelial defects of the cornea

D Diaz‐Valle, B Burgos‐Blasco… - Acta …, 2022 - Wiley Online Library
Purpose To investigate the effect of topical insulin on epithelization in persistent epithelial
defects (PED) refractory to usual treatment compared to autologous serum. Design …