5-Fluorouracil: a narrative review on the role of regulatory mechanisms in driving resistance to this chemotherapeutic agent
5-fluorouracil (5-FU) is among the mostly administrated chemotherapeutic agents for a wide
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …
Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications
Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …
An emerging class of long non-coding RNA with oncogenic role arises from the snoRNA host genes
The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which
are reported in many studies as being overexpressed in various cancers. With very few …
are reported in many studies as being overexpressed in various cancers. With very few …
Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs
W Jiang, J Xia, S Xie, R Zou, S Pan, Z Wang… - Drug Resistance …, 2020 - Elsevier
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …
LncRNA signature in colorectal cancer
Colorectal cancer (CRC) is among the most frequent cancers and is associated with high
mortality particularly when being diagnosed in advanced stages. Although several …
mortality particularly when being diagnosed in advanced stages. Although several …
Long noncoding RNA TYKRIL plays a role in pulmonary hypertension via the p53-mediated regulation of PDGFRβ
CM Zehendner, C Valasarajan, A Werner… - American Journal of …, 2020 - atsjournals.org
Rationale: Long noncoding RNAs (lncRNAs) are emerging as important regulators of
diverse biological functions. Their role in pulmonary arterial hypertension (PAH) remains to …
diverse biological functions. Their role in pulmonary arterial hypertension (PAH) remains to …
Reverse-genetics studies of lncRNAs—what we have learnt and paths forward
F Gao, Y Cai, P Kapranov, D Xu - Genome biology, 2020 - Springer
Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
LncRNA SNHG15 regulates EGFR-TKI acquired resistance in lung adenocarcinoma through sponging miR-451 to upregulate MDR-1
J Huang, B Pan, G Xia, J Zhu, C Li, J Feng - Cell death & disease, 2020 - nature.com
Lung adenocarcinoma (LUAD) is the main component of non-small-cell lung cancer
(NSCLC) and causes a great health concern globally. The top priority of LUAD treatment is …
(NSCLC) and causes a great health concern globally. The top priority of LUAD treatment is …
[HTML][HTML] Comprehensive landscape and future perspectives of long noncoding RNAs (lncRNAs) in colorectal cancer (CRC): Based on a bibliometric analysis
J He, W Wu - Non-coding RNA Research, 2023 - Elsevier
This review aimed to use bibliometric analysis to sort out, analyze and summarize the
knowledge foundation and hot topics in the field of long noncoding RNAs (lncRNAs) in …
knowledge foundation and hot topics in the field of long noncoding RNAs (lncRNAs) in …
Role of non-coding RNAs in colorectal cancer: focus on long non-coding RNAs
Simple Summary Non-coding RNAs are a type of RNA that is not translated into proteins.
They play important roles in several cellular processes, mainly in the regulation of genetic …
They play important roles in several cellular processes, mainly in the regulation of genetic …