[HTML][HTML] The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders

K Socała, U Doboszewska, A Szopa, A Serefko… - Pharmacological …, 2021 - Elsevier
Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional
communication between the gut and the brain suggesting that the gut microbes may shape …

The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options

Q Wang, Y Luo, K Ray Chaudhuri, R Reynolds, EK Tan… - Brain, 2021 - academic.oup.com
Parkinson's disease is a common neurodegenerative disorder in which gastrointestinal
symptoms may appear prior to motor symptoms. The gut microbiota of patients with …

Microbiome, probiotics and neurodegenerative diseases: deciphering the gut brain axis

S Westfall, N Lomis, I Kahouli, SY Dia, SP Singh… - Cellular and molecular …, 2017 - Springer
The gut microbiota is essential to health and has recently become a target for live bacterial
cell biotherapies for various chronic diseases including metabolic syndrome, diabetes …

Mitochondrial ROS signaling in organismal homeostasis

GS Shadel, TL Horvath - Cell, 2015 - cell.com
Generation, transformation, and utilization of organic molecules in support of cellular
differentiation, growth, and maintenance are basic tenets that define life. In eukaryotes …

[HTML][HTML] Ghrelin

TD Müller, R Nogueiras, ML Andermann… - Molecular …, 2015 - Elsevier
Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

Microbiome-gut-brain axis and toll-like receptors in Parkinson's disease

V Caputi, MC Giron - International journal of molecular sciences, 2018 - mdpi.com
Parkinson's disease (PD) is a progressively debilitating neurodegenerative disease
characterized by α-synucleinopathy, which involves all districts of the brain-gut axis …

Changes of colonic bacterial composition in Parkinson's disease and other neurodegenerative diseases

S Gerhardt, MH Mohajeri - Nutrients, 2018 - mdpi.com
In recent years evidence has emerged that neurodegenerative diseases (NDs) are strongly
associated with the microbiome composition in the gut. Parkinson's disease (PD) is the most …

The effects of Δ9-tetrahydrocannabinol on the dopamine system

MAP Bloomfield, AH Ashok, ND Volkow, OD Howes - Nature, 2016 - nature.com
The effects of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis,
are a pressing concern for global mental health. Patterns of cannabis use are changing …

PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders

S Jamwal, JK Blackburn, JD Elsworth - Pharmacology & Therapeutics, 2021 - Elsevier
Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Neuronal regulation of energy homeostasis: beyond the hypothalamus and feeding

MJ Waterson, TL Horvath - Cell metabolism, 2015 - cell.com
The essential role of the brain in maintaining energy homeostasis has motivated the drive to
define the neural circuitry that integrates external and internal stimuli to enact appropriate …