Background: Malignant glial tumors, including glioblastoma multiforme, account for 15–20%
of pediatric CNS malignancies. They are most resistant to therapy and are associated with a …

Mesenchymal stem cells (MSCs) possess a set of several fairly unique properties which
make them ideally suited both for cellular therapies/regenerative medicine, and as vehicles …

Ethical and moral issues rule out the use of human induced pluripotent stem cells (iPSCs) in
chimera studies that would determine the full extent of their reprogrammed state, instead …

Mesenchymal stromal cells (MSCs) possess several fairly unique properties that, when
combined, make them ideally suited for cellular-based immunotherapy and as vehicles for …

Premature ovarian failure (POF) is a long-term adverse effect of chemotherapy treatment.
However, current available treatment regimens are not optimal. Emerging evidence …

Study Design. Changes in gene expression profile and cell fusion of mesenchymal stem
cells (MSC) and nucleus pulposus cells (NPC) after coculture were analyzed. Objective. To …

Human embryonic stem cells (hESC) have the potential to produce all of the cells in the
body. They are able to self-renew indefinitely, potentially making them a source for large …

The systemic administration of oncolytic virus (OV) is often inefficient due to clearance of the
virus by host defense mechanism and spurious targeting of non-cancer tissues through the …

Pigs are increasingly being recognized as good large-animal models for translational
research, linking basic science to clinical applications in order to establish novel …

Somatic cell reprogramming has generated enormous interest after the first report by
Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells …