Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review

K Renu, R Chakraborty, H Myakala, R Koti… - Chemosphere, 2021 - Elsevier
Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …

Cadmium and atherosclerosis: A review of toxicological mechanisms and a meta-analysis of epidemiologic studies

AA Tinkov, T Filippini, OP Ajsuvakova… - Environmental …, 2018 - Elsevier
Cadmium has been proposed to be the one of the factors of atherosclerosis development,
although the existing data are still controversial. The primary objective of the present study is …

The mechanism of the cadmium-induced toxicity and cellular response in the liver

V Souza-Arroyo, JJ Fabián, L Bucio-Ortiz… - Toxicology, 2022 - Elsevier
Cadmium is a toxic element to which man can be exposed at work or in the environment.
Cd's most salient toxicological property is its exceptionally long half-life in the human body …

Association between heavy metals, high-sensitivity C-reaction protein and 10-year risk of cardiovascular diseases among adult Korean population

HD Nguyen, H Oh, NHM Hoang, MS Kim - Scientific Reports, 2021 - nature.com
The prevalence of cardiovascular diseases (CVDs) in Korea tends to be increasing. It has
worsened during the COVID-19 pandemic. Increasing evidence shows heavy metals are …

Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review

T Farkhondeh, O Mehrpour, F Forouzanfar… - … Science and Pollution …, 2020 - Springer
Organophosphorus pesticides (OPs) are widely used for controlling pests worldwide. The
inhibitory effects of these pesticides on acetylcholinesterase lead to neurotoxic damages …

[HTML][HTML] Molecular mechanism-based therapeutic properties of honey

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2020 - Elsevier
Honey and its phenolic compounds specifically chrysin are focused as nutritional
supplements and likewise as valued phytochemicals, nutraceuticals, and …

[HTML][HTML] Endocrine disruption and obesity: A current review on environmental obesogens

R Gupta, P Kumar, N Fahmi, B Garg, S Dutta… - Current Research in …, 2020 - Elsevier
Obesity represents an important public health concern because it substantially increases the
risk of multiple chronic diseases and thereby contributing to a decline in both quality of life …

The role of arsenic in obesity and diabetes

T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
As many individuals worlwide are exposed to arsenic, it is necessary to unravel the role of
arsenic in the risk of obesity and diabetes. Therefore, the present study reviewed the effects …

Organophosphorus compounds and MAPK signaling pathways

T Farkhondeh, O Mehrpour, C Buhrmann… - International journal of …, 2020 - mdpi.com
The molecular signaling pathways that lead to cell survival/death after exposure to
organophosphate compounds (OPCs) are not yet fully understood. Mitogen-activated …

[HTML][HTML] Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and …

J Gu, A Kong, C Guo, J Liu, K Li, Z Ren, Y Zhou… - Ecotoxicology and …, 2022 - Elsevier
Abstract Cadmium ion (Cd 2+) exposure has been reported to associate with the prevalence
of dyslipidemia, and contribute to the initiation and progression of nonalcoholic fatty liver …