Newer biologic and small-molecule therapies for inflammatory bowel disease

DC Baumgart, C Le Berre - New England Journal of Medicine, 2021 - Mass Medical Soc
Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory
bowel disease. This review covers newer treatments that reflect our understanding of the …

25 years of anti-TNF treatment for inflammatory bowel disease: lessons from the past and a look to the future

GR D'Haens, S van Deventer - Gut, 2021 - gut.bmj.com
Anti-tumour necrosis factor (TNF) antibodies have been widely used for approximately 25
years now. The first clinical observations in patients with refractory Crohn's disease rapidly …

The medical management of paediatric Crohn's disease: an ECCO-ESPGHAN guideline update

PF Van Rheenen, M Aloi, A Assa… - Journal of Crohn's …, 2021 - academic.oup.com
Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

3rd European evidence-based consensus on the diagnosis and management of Crohn's disease 2016: part 2: surgical management and special situations

P Gionchetti, A Dignass, S Danese… - Journal of Crohn's …, 2017 - academic.oup.com
This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Tumor necrosis factor inhibitors for inflammatory bowel disease

OH Nielsen, MA Ainsworth - New England Journal of Medicine, 2013 - Mass Medical Soc
Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Aktualisierte S3-Leitlinie „Diagnostik und Therapie des Morbus Crohn “der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten …

A Sturm, R Atreya, D Bettenworth… - Zeitschrift für …, 2022 - thieme-connect.com
Im Jahr 2019 wurden etwa 25 500 Patient* innen mit M. Crohn im Krankenhaus stationär
behandelt [1]. Meistens tritt die Erkrankung in der Adoleszenz und im jungen …

Male gender, active smoking and previous intestinal resection are risk factors for post‐operative endoscopic recurrence in Crohn's disease: results from a prospective …

C Auzolle, S Nancey, ML Tran‐Minh… - Alimentary …, 2018 - Wiley Online Library
Background After ileocaecal resection for Crohn's disease (CD), inflammatory lesions
frequently recur on the anastomosis and/or on the neo‐terminal ileum. Aim To identify …

Anti-TNF agents and new biological agents (Vedolizumab and Ustekinumab) in the prevention and treatment of postoperative recurrence after surgery in Crohn's …

JP Gisbert, M Chaparro - Drugs, 2023 - Springer
Surgery for Crohn's disease (CD) is not curative, as postoperative recurrence (POR) after
ileocolonic resection is the rule in the absence of prophylactic treatment. In the present …

Visceral adiposity predicts post‐operative Crohn's disease recurrence

DQ Holt, GT Moore, BJG Strauss… - Alimentary …, 2017 - Wiley Online Library
Background Excessive visceral adipose tissue has been associated with poorer outcomes in
patients with inflammatory bowel disease. Aim To determine whether body composition is …

Endoscopic postoperative recurrence in Crohn's disease after curative ileocecal resection with early prophylaxis by anti-TNF, vedolizumab or ustekinumab: a real …

H Yanai, A Kagramanova, O Knyazev… - Journal of Crohn's …, 2022 - academic.oup.com
Background Endoscopic-post-operative-recurrence [ePOR] in Crohn's disease [CD] after
ileocecal resection [ICR] is a major concern. We aimed to evaluate the effectiveness of early …