The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

The global incidence of human papillomavirus–positive (HPV+) head and neck squamous
cell carcinoma (HNSCC) has surged in recent decades, with HPV+ HNSCC accounting for> …

This study evaluated the impact of cell debris and 7-day room temperature storage on the
quality and yield of transrenal DNA. Archived urine specimens collected from five …

Liquid biopsy utilizing cell-free DNA (cfDNA) has become an emergent field of study for
cancer screening and monitoring. While blood-based liquid biopsy has been investigated …

Purpose: Current diagnostic methods for endometrial cancer lack specificity, leading to
many women undergoing invasive procedures. The aim of this study was to evaluate …

BACKGROUND Transrenal cell-free tumor DNA (TR-ctDNA), which transits from the
bloodstream into urine, has the potential to enable noninvasive cancer detection for a wide …

High cancer mortality rates and the rising cancer burden worldwide drive the development of
innovative methods in order to advance cancer diagnostics. Urine contains a viable source …

Background Urine holds promise as a source for cell‐free DNA (cfDNA) analysis of cancer
genetics due to its nature as a self‐collectable biospecimen available in large quantities …

Simple Summary In the field of cancer, body fluids such as urine are gaining interest for non-
invasive cancer detection and screening. To enable home collection, sample shipment, and …

The rates of human papillomavirus-positive oropharyngeal cancer (HPV-OPC) are rising
worldwide and in the United States, particularly in rural regions including Appalachia. Rural …