Pathophysiological roles of peroxynitrite in circulatory shock
Peroxynitrite is a reactive oxidant produced from nitric oxide and superoxide, which reacts
with proteins, lipids, and DNA, and promotes cytotoxic and proinflammatory responses …
with proteins, lipids, and DNA, and promotes cytotoxic and proinflammatory responses …
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS–NO pathway
S Guo, E Bezard, B Zhao - Free Radical Biology and Medicine, 2005 - Elsevier
Green tea polyphenols (GTP) are thought to help prevent oxidative stress-related diseases,
such as cancer, cardiovascular disease, neurodegenerative disease, and aging. We here …
such as cancer, cardiovascular disease, neurodegenerative disease, and aging. We here …
Effects of ω-3 PUFA-rich oil supplementation on cardiovascular morphology and aortic vascular reactivity of adult male rats submitted to an hypercholesterolemic diet
M Mendes Furtado, JÉ Lima Rocha… - Biology, 2022 - mdpi.com
Simple Summary Currently, processed and ultraprocessed foods represent a significant
component of the diet of modern societies, increasing the risk of developing obesity …
component of the diet of modern societies, increasing the risk of developing obesity …
Hypersensitivity of BKCa to Ca2+ Sparks Underlies Hyporeactivity of Arterial Smooth Muscle in Shock
G Zhao, Y Zhao, B Pan, J Liu, X Huang… - Circulation …, 2007 - Am Heart Assoc
Large conductance Ca2+-activated K+ channels (BKCa) play a critical role in blood
pressure regulation by tuning the vascular smooth muscle tone, and hyposensitivity of BKCa …
pressure regulation by tuning the vascular smooth muscle tone, and hyposensitivity of BKCa …
Angiopoietins regulate vascular reactivity after haemorrhagic shock in rats through the Tie2-nitric oxide pathway
J Xu, D Lan, T Li, G Yang, L Liu - Cardiovascular research, 2012 - academic.oup.com
Aims Vascular reactivity shows biphasic changes after severe trauma or shock. Our aim was
to elucidate the mechanisms of biphasic-changed vascular reactivity after haemorrhagic …
to elucidate the mechanisms of biphasic-changed vascular reactivity after haemorrhagic …
Hemorheologic events in severe shock
KS Zhao - Biorheology, 2005 - content.iospress.com
Persistent low perfusion and low blood pressure are the two major events in the
pathogenesis of irreversible shock. This review is focused on our recent study on the …
pathogenesis of irreversible shock. This review is focused on our recent study on the …
Calcium mobilization is required for peroxynitrite-mediated enhancement of spontaneous transient outward currents in arteriolar smooth muscle cells
B Pan, G Zhao, X Huang, K Zhao - Free Radical Biology and Medicine, 2004 - Elsevier
Transiently local release of Ca2+ from the sarcoplasmic reticulum (SR) activates nearby
Ca2+-activated K+ channels to produce spontaneous transient outward currents (STOCs) in …
Ca2+-activated K+ channels to produce spontaneous transient outward currents (STOCs) in …
Inhibition of L-type calcium channels in arteriolar smooth muscle cells is involved in the pathogenesis of vascular hyporeactivity in severe shock
Q Zhao, K Zhao - Shock, 2007 - journals.lww.com
The objective was to investigate the changes in the function of L-type calcium (L-Ca 2+)
channels of arteriolar smooth muscle cells (ASMCs) in the genesis of vascular hyporeactivity …
channels of arteriolar smooth muscle cells (ASMCs) in the genesis of vascular hyporeactivity …
Hemorrhagic preconditioning improves vascular reactivity after hemorrhagic shock by activation of PKC [alpha] and PKC [epsilon] via the adenosine A1 receptor in …
J Xu, D Lan, G Yang, T Li, L Liu - Journal of Trauma and Acute …, 2013 - journals.lww.com
BACKGROUND: Our previous study demonstrated that protein kinase C (PKC) has an
important protective role on vascular reactivity and calcium sensitivity after shock. Here, we …
important protective role on vascular reactivity and calcium sensitivity after shock. Here, we …