Fungal infections impact the lives of at least 12 million people every year, killing over 1.5
million. Wide-spread use of fungicides and prophylactic antifungal therapy have driven …

Germination of conidia is an essential process within the Aspergillus life cycle and plays a
major role during the infection of hosts. Conidia are able to avoid detection by the majority of …

Aspergillus fumigatus is a ubiquitous environmental mold that can cause severe disease in
immunocompromised patients and chronic disease in individuals with underlying lung …

Aspergillus fumigatus is a ubiquitous fungus and the main agent of aspergillosis, a common
fungal infection in the immunocompromised population. Triazoles such as itraconazole and …

Aspergillus fumigatus is the most common cause of invasive fungal mold infections in
immunocompromised individuals. Current antifungal treatment relies heavily on the triazole …

Invasive fungal infections in humans caused by several Candida species, increased
considerably in immunocompromised or critically ill patients, resulting in substantial …

Invasive fungal infections are a strong contributor to healthcare costs, morbidity and
mortality, especially amongst hospitalized patients. Historically, Candida was responsible for …

Azole drugs target fungal sterol biosynthesis and are used to treat millions of human fungal
infections each year. Resistance to azole drugs has emerged in multiple fungal pathogens …

Triazole-resistant Aspergillus fumigatus is a global health concern. In general, each triazole
resistance pattern caused by the specified amino acid substitution of Cyp51A has a typical …

Members of Fusarium solani species complex (FSSC) are cosmopolitan filamentous fungi
responsible for invasive fungal infections in immunocompromised patients. Despite the …