Aortic disease is a significant cause of death in developed countries. The most common
forms of aortic disease are aneurysm, dissection, atherosclerotic occlusion and ageing …

Biomechanical factors play fundamental roles in the natural history of abdominal aortic
aneurysms (AAAs) and their responses to treatment. Advances during the past two decades …

This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

The established method of polarized microscopy in combination with a universal stage is
used to determine the layer-specific distributed collagen fibre orientations in 11 human non …

The complex network structure of elastin and collagen extracellular matrix (ECM) forms the
primary load bearing components in the arterial wall. The structural and mechanobiological …

Many treatments for cardiovascular diseases include an endovascular insertion of stents or
stent grafts into arteries, a procedure which may cause high tissue stresses and even …

The stiffness and structural integrity of the arterial wall depends primarily on the organization
of the extracellular matrix and the cells that fashion and maintain this matrix. Fundamental to …

This paper provides the first analysis of the three-dimensional state of residual stress and
stretch in an artery wall consisting of three layers (intima, media and adventitia), modelled as …

The structural protein elastin endows large arteries with unique biological functionality and
mechanical integrity, hence its disorganization, fragmentation, or degradation can have …

OBJECTIVES: The acute dissection of an ascending thoracic aortic aneurysm (ATAA)
represents a devastating separation of elastic layers occurring when the hemodynamic …