Mitochondria are among the most important cell organelles involved in the regulation of
intracellular calcium homeostasis. During the last decade, a number of molecular structures …

The presence of biological rhythms is a characteristic of all living organisms. Over the past
60 years, scientists around the world have accumulated a huge amount of data on rhythmic …

In vitro models serve as a tool for studies of steatosis. Palmitic and oleic acids can induce
steatosis in cultured hepatocytes. The aim of our study was to verify steatogenic and …

Appetite regulation by nutritional intervention is required early in life that involves the anti-
aging gene Sirtuin 1 (Sirt 1) with Sirt 1 maintenance of other cellular anti-aging genes …

Mitochondria play an essential role in both cell health and death. Increasing experimental
evidence suggests that mitochondria are involved in active control of cell death processes at …

Lipid overload resulting in lipotoxicity is prominent in a number of chronic diseases and has
been associated with cellular dysfunction and cell death. This study characterizes palmitic …

We review research investigating mitochondrial damage during heart and brain ischaemia,
focusing on the mechanisms and consequences of ischaemia‐induced and/or reperfusion …

A sharp increase in the permeability of the mitochondrial inner membrane known as
mitochondrial permeability transition (or mPT) occurs in mitochondria under the conditions of …

The plant Typhonium flagelliforme, commonly known as “rodent tuber” in Malaysia, is often
used as a health supplement and traditional remedy for alternative cancer therapies …

Benzbromarone is an uricosuric structurally related to amiodarone and a known
mitochondrial toxicant. The aim of the current study was to improve our understanding in the …