Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling
Y Wang, R Branicky, A Noë, S Hekimi - Journal of Cell Biology, 2018 - rupress.org
Superoxide dismutases (SODs) are universal enzymes of organisms that live in the
presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen …
presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen …
Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
[HTML][HTML] ROS scavenging Mn 3 O 4 nanozymes for in vivo anti-inflammation
Reactive oxygen species (ROS)-induced oxidative stress is linked to various diseases,
including cardiovascular disease and cancer. Though highly efficient natural ROS …
including cardiovascular disease and cancer. Though highly efficient natural ROS …
[PDF][PDF] Classification of metal-based drugs according to their mechanisms of action
Metal-based drugs and imaging agents are extensively used in the clinic for the treatment
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …
[HTML][HTML] Oxidative stress, inflammation and colorectal cancer: An overview
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …
[HTML][HTML] Superoxide dismutase administration: A review of proposed human uses
AC Rosa, D Corsi, N Cavi, N Bruni, F Dosio - Molecules, 2021 - mdpi.com
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …
[HTML][HTML] Functions and dysfunctions of nitric oxide in brain
P Picón-Pagès, J Garcia-Buendia, FJ Munoz - Biochimica et Biophysica …, 2019 - Elsevier
Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …
flow and also has important roles in intracellular signaling in neurons from the regulation of …
[HTML][HTML] Superoxide dismutases and superoxide reductases
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …
Mediation of oxidative stress toxicity induced by pyrethroid pesticides in fish
Organophosphate and organochlorine pesticides are banned in most countries because
they cause high toxicity and bioaccumulation in non-target organisms. Pyrethroid pesticides …
they cause high toxicity and bioaccumulation in non-target organisms. Pyrethroid pesticides …
Self‐assembly of multi‐nanozymes to mimic an intracellular antioxidant defense system
Y Huang, Z Liu, C Liu, E Ju, Y Zhang… - Angewandte …, 2016 - Wiley Online Library
In this work, for the first time, we constructed a novel multi‐nanozymes cooperative platform
to mimic intracellular antioxidant enzyme‐based defense system. V2O5 nanowire served as …
to mimic intracellular antioxidant enzyme‐based defense system. V2O5 nanowire served as …