Chitosan: a potential biopolymer in drug delivery and biomedical applications

N Desai, D Rana, S Salave, R Gupta, P Patel… - Pharmaceutics, 2023 - mdpi.com
Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has
surfaced as a material of promise for drug delivery and biomedical applications. Different …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

A state-of-the-art review on the recent advances of niosomes as a targeted drug delivery system

S Yasamineh, P Yasamineh, HG Kalajahi… - International journal of …, 2022 - Elsevier
The buildup of nonionic surfactants in the aqueous environment produces niosomes. The
usage of niosomes is becoming increasingly frequent due to their sustainability, low cost of …

Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

MH Elkomy, AA Ali, HM Eid - Journal of Controlled Release, 2022 - Elsevier
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Surface modification of lipid-based nanocarriers: a potential approach to enhance targeted drug delivery

S Priya, VM Desai, G Singhvi - ACS omega, 2022 - ACS Publications
Nanocarriers have the utmost significance for advancements in drug delivery and
nanomedicine technology. They are classified as polymer-based nanocarriers, lipid-based …

Surface-modified bilosomes nanogel bearing a natural plant alkaloid for safe management of rheumatoid arthritis inflammation

MH Elkomy, NK Alruwaili, M Elmowafy, K Shalaby… - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

Niosome as an effective nanoscale solution for the treatment of microbial infections

M Barani, F Paknia, M Roostaee… - BioMed Research …, 2023 - Wiley Online Library
Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …

Intranasal delivery of granisetron to the brain via nanostructured cubosomes-based in situ gel for improved management of chemotherapy-induced emesis

EM Eissa, MH Elkomy, HM Eid, AA Ali, MAS Abourehab… - Pharmaceutics, 2022 - mdpi.com
This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to
better manage chemotherapy-induced emesis. Glycerol monooleate (GMO), Poloxamer 407 …

Novel bile salt stabilized vesicles-mediated effective topical delivery of diclofenac sodium: A new therapeutic approach for pain and inflammation

TM Mahmoud, MM Nafady, HO Farouk, DM Mahmoud… - Pharmaceuticals, 2022 - mdpi.com
The oral delivery of diclofenac sodium (DNa), a non-steroidal analgesic, anti-inflammatory
drug, is associated with various gastrointestinal side effects. The aim of the research was to …

Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: Improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic …

MH Elkomy, HM Eid, M Elmowafy, K Shalaby… - Drug …, 2022 - Taylor & Francis
Diabetes mellitus is a life-threatening metabolic disease. At the moment, there is no effective
treatment available to combat it. In this study, we aimed to develop berberine-loaded …