A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …
health problems across the lifespan. Increasing evidence supports the hypothesis that …
[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …
represent a mechanism for the biological embedding of early traumatic experiences …
Understanding the molecular mechanisms underpinning gene by environment interactions in psychiatric disorders: the FKBP5 model
Epidemiologic and genetic studies suggest common environmental and genetic risk factors
for a number of psychiatric disorders, including depression, bipolar disorder, and …
for a number of psychiatric disorders, including depression, bipolar disorder, and …
Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health
This review integrates scientific knowledge obtained over the past few decades on the
biological mechanisms that contribute to the profound association between exposure to …
biological mechanisms that contribute to the profound association between exposure to …
Epigenetic pathways in human disease: the impact of DNA methylation on stress-related pathogenesis and current challenges in biomarker development
MA Argentieri, S Nagarajan, B Seddighzadeh… - …, 2017 - thelancet.com
HPA axis genes implicated in glucocorticoid regulation play an important role in regulating
the physiological impact of social and environmental stress, and have become a focal point …
the physiological impact of social and environmental stress, and have become a focal point …
The role of epigenetics in psychological resilience
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
Adverse childhood events and health biomarkers: a systematic review
Background: This systematic review aimed to summarize evidence reporting epigenetic
and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in …
and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in …
Epigenetic programming by stress and glucocorticoids along the human lifespan
AS Zannas, GP Chrousos - Molecular psychiatry, 2017 - nature.com
Psychosocial stress triggers a set of behavioral, neural, hormonal, and molecular responses
that can be a driving force for survival when adaptive and time-limited, but may also …
that can be a driving force for survival when adaptive and time-limited, but may also …
Advance in stress for depressive disorder
Y Ding, J Dai - Depressive Disorders: Mechanisms, Measurement and …, 2019 - Springer
Stress is an adaptive response to environment aversive stimuli and a common life
experience of one's daily life. Chronic or excessive stress especially that happened in early …
experience of one's daily life. Chronic or excessive stress especially that happened in early …
Hsp90 and FKBP51: complex regulators of psychiatric diseases
M Criado-Marrero, T Rein… - … of the Royal …, 2018 - royalsocietypublishing.org
Mood disorders affect nearly a quarter of the world's population. Therefore, understanding
the molecular mechanisms underlying these conditions is of great importance. FK-506 …
the molecular mechanisms underlying these conditions is of great importance. FK-506 …