Highlights•There are several promising techniques for processing calcium imaging
data.•Comparing the accuracy of these methods is difficult, due to lack of ground truth.•The …

Calcium imaging is a popular tool among neuroscientists because of its capability to monitor
in vivo large neural populations across weeks with single neuron and single spike …

Neural stem/progenitor cell (NSPC) grafts can integrate into sites of spinal cord injury (SCI)
and generate neuronal relays across lesions that can provide functional benefit. To …

The characteristics of the sleep drivers and the mechanisms through which sleep relieves
the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA …

Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular
function of sleep is unknown, and there is no conserved molecular marker to define sleep …

Methods for one-photon fluorescent imaging of calcium dynamics can capture the activity of
hundreds of neurons across large fields of view at a low equipment complexity and cost. In …

Simultaneous recordings of large populations of neurons in behaving animals allow detailed
observation of high-dimensional, complex brain activity. However, experimental approaches …

Previous studies suggest that the brain operates at a critical point in which phases of order
and disorder coexist, producing emergent patterned dynamics at all scales and optimizing …

Glial cells support the function of neurons. Recent evidence shows that astrocytes are also
involved in brain computations. To explore whether and how their excitable nature affects …

Abstract Information for organismal patterning can come from a variety of sources. We
investigate the possibility that instructive influences for normal embryonic development are …