According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Biological systems are composed of numerous components of which proteins are of
particularly high functional significance. Network models are useful abstractions for studying …

Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism
of telomere elongation that controls proliferation in subsets of aggressive cancer. Recent …

Affinity purification coupled with mass spectrometry (AP-MS) is a widely used approach for
the identification of protein-protein interactions. However, for any given protein of interest …

Polycomb group (PcG) proteins are major determinants of gene silencing and epigenetic
memory in higher eukaryotes. Here, we systematically mapped the human PcG complexome …

Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …

Chromosomal translocations that generate in-frame oncogenic gene fusions are notable
examples of the success of targeted cancer therapies,,. We have previously described gene …

A changing climate is altering many ocean properties that consequently will modify marine
productivity. Previous phytoplankton manipulation studies have focused on individual or …

Mechanical stimuli, such as wind, rain, and touch affect plant development, growth, pest
resistance, and ultimately reproductive success. Using water spray to simulate rain, we …

Polycomb repressive complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic
regulation of transcription during cellular differentiation, stem cell pluripotency and …