Protein analysis by shotgun/bottom-up proteomics
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
Applications of targeted proteomics in systems biology and translational medicine
Biological systems are composed of numerous components of which proteins are of
particularly high functional significance. Network models are useful abstractions for studying …
particularly high functional significance. Network models are useful abstractions for studying …
RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
N Kaminski, AR Wondisford, Y Kwon, ML Lynskey… - Molecular cell, 2022 - cell.com
Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism
of telomere elongation that controls proliferation in subsets of aggressive cancer. Recent …
of telomere elongation that controls proliferation in subsets of aggressive cancer. Recent …
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
D Mellacheruvu, Z Wright, AL Couzens, JP Lambert… - Nature …, 2013 - nature.com
Affinity purification coupled with mass spectrometry (AP-MS) is a widely used approach for
the identification of protein-protein interactions. However, for any given protein of interest …
the identification of protein-protein interactions. However, for any given protein of interest …
A high-density map for navigating the human polycomb complexome
Polycomb group (PcG) proteins are major determinants of gene silencing and epigenetic
memory in higher eukaryotes. Here, we systematically mapped the human PcG complexome …
memory in higher eukaryotes. Here, we systematically mapped the human PcG complexome …
ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies
Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …
acquisition technique, quantification tool and processing method has emerged as the …
A metabolic function of FGFR3-TACC3 gene fusions in cancer
Chromosomal translocations that generate in-frame oncogenic gene fusions are notable
examples of the success of targeted cancer therapies,,. We have previously described gene …
examples of the success of targeted cancer therapies,,. We have previously described gene …
Physiological responses of a Southern Ocean diatom to complex future ocean conditions
A changing climate is altering many ocean properties that consequently will modify marine
productivity. Previous phytoplankton manipulation studies have focused on individual or …
productivity. Previous phytoplankton manipulation studies have focused on individual or …
A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels
A Van Moerkercke, O Duncan… - Proceedings of the …, 2019 - National Acad Sciences
Mechanical stimuli, such as wind, rain, and touch affect plant development, growth, pest
resistance, and ultimately reproductive success. Using water spray to simulate rain, we …
resistance, and ultimately reproductive success. Using water spray to simulate rain, we …
The central role of EED in the orchestration of polycomb group complexes
Polycomb repressive complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic
regulation of transcription during cellular differentiation, stem cell pluripotency and …
regulation of transcription during cellular differentiation, stem cell pluripotency and …