A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes

VR Aroda, L Blonde, RE Pratley - Reviews in Endocrine and Metabolic …, 2022 - Springer
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) were first
introduced for the treatment of type 2 diabetes (T2D) in 2005. Despite the high efficacy and …

Oral GLP-1 analogue: perspectives and impact on atherosclerosis in type 2 diabetic patients

JFK Saraiva, D Franco - Cardiovascular Diabetology, 2021 - Springer
Cardiovascular events related to atherosclerosis are responsible for high morbidity and
mortality among patients with type 2 diabetes. Improvement in care, especially in early …

A small-molecule oral agonist of the human glucagon-like peptide-1 receptor

DA Griffith, DJ Edmonds, JP Fortin… - Journal of Medicinal …, 2022 - ACS Publications
Peptide agonists of the glucagon-like peptide-1 receptor (GLP-1R) have revolutionized
diabetes therapy, but their use has been limited because they require injection. Herein, we …

Predictors of medication adherence in patients with type 2 diabetes mellitus

SM Curkendall, N Thomas, KF Bell… - … medical research and …, 2013 - Taylor & Francis
Objective: Medical professionals are often challenged by lack of patient compliance with
pharmaceutical treatments. Research has shown that patients with diabetes have one of the …

Comorbidities, health-related quality of life, and work productivity among people with obstructive sleep apnea with excessive sleepiness: findings from the 2016 US …

C Stepnowsky, KF Sarmiento, S Bujanover… - Journal of Clinical …, 2019 - jcsm.aasm.org
Study Objectives: Few population-based studies have explored how excessive sleepiness
(ES) contributes to burden of illness among patients with obstructive sleep apnea (OSA) …

Patients' preferences for once‐daily oral versus once‐weekly injectable diabetes medications: the REVISE study

K Boye, M Ross, R Mody, M Konig… - Diabetes, Obesity and …, 2021 - Wiley Online Library
Aims To understand patient preferences for once‐daily oral versus once‐weekly injectable
type 2 diabetes mellitus (T2DM) medication administration profiles, and reasons for their …

Glucagon‐Like Peptide‐1 Receptor Agonists for Chronic Weight Management

M Wojtara, A Mazumder, Y Syeda… - Advances in …, 2023 - Wiley Online Library
Rates of obesity have risen over the past few decades. Subsequently, the popularity of the
pharmaceutical weight‐loss drug market has grown over the past few years to meet growing …

[HTML][HTML] Testing the feasibility and dietary impact of a “produce prescription” program for adults with undermanaged type 2 diabetes and food insecurity in Australia

JHY Wu, K Trieu, D Coyle, L Huang, N Wijesuriya… - The Journal of …, 2022 - Elsevier
Background There is growing interest in Food is Medicine programs that incorporate food-
based interventions into health care for patients with diet-related conditions. Objectives We …

The REVIVE (REal Women's VIews of Treatment Options for Menopausal Vaginal ChangEs) survey in Europe: country-specific comparisons of postmenopausal …

RE Nappi, S Palacios, M Particco, N Panay - Maturitas, 2016 - Elsevier
Objectives To achieve a better comprehension of the variability of perceptions, experiences
and needs in terms of sexual and vaginal health in postmenopausal women (PMW) from …

[HTML][HTML] Patient-centric design for peptide delivery: Trends in routes of administration and advancement in drug delivery technologies

AN Ganesh, C Heusser, S Garad… - Medicine in Drug …, 2021 - Elsevier
Utilizing peptides as therapeutic agents is considered an attractive approach for the
treatment of various diseases due to their high binding and selectivity to novel drug targets …