[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Considerations for polymers used in ocular drug delivery

MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Gel/hydrogel‐based in situ biomaterial platforms for cancer postoperative treatment and recovery

Y Feng, Z Zhang, W Tang, Y Dai - Exploration, 2023 - Wiley Online Library
Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …

Nano-based formulations of curcumin: Elucidating the potential benefits and future prospects in skin cancer

C Ratan, AM Arian, R Rajendran… - Biomedical …, 2023 - iopscience.iop.org
Skin cancer refers to any malignant lesions that occur in the skin and are observed
predominantly in populations of European descent. Conventional treatment modalities such …

Hyaluronic acid-based nanoparticles to deliver drugs to the ocular posterior segment

H Jiang, Z Xu - Drug Delivery, 2023 - Taylor & Francis
Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …

Optimization of an injectable hydrogel depot system for the controlled release of retinal-targeted hybrid nanoparticles

I Ottonelli, A Bighinati, E Adani, F Loll, R Caraffi… - Pharmaceutics, 2022 - mdpi.com
A drawback in the development of treatments that can reach the retina is the presence of
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …

Curcumin doped zeolitic imidazolate framework nanoplatforms as multifunctional nanocarriers for tumor chemo/immunotherapy

J Liu, S Liu, Y Wu, X Xu, Q Li, M Yang, A Gong… - Biomaterials …, 2022 - pubs.rsc.org
Curcumin as a hydrophobic polyphenol has great potential for tumor therapy, yet its rapid
degradation and hydrophobicity severely impair its therapeutic effect in the clinic. Herein, we …

[HTML][HTML] In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma

Y Liu, W Ma, P Zhou, Q Wen, Q Wen, Y Lu… - Biomedicine & …, 2023 - Elsevier
Chemotherapy is one of the main therapeutic strategies for the treatment of malignant
melanoma. Conventional chemotherapeutic agents often lack targeting abilities, and efficacy …

From molecular biology to novel immunotherapies and nanomedicine in uveal melanoma

KJ Synoradzki, N Paduszyńska, M Solnik, MD Toro… - Current …, 2024 - mdpi.com
Molecular biology studies of uveal melanoma have resulted in the development of novel
immunotherapy approaches including tebentafusp—a T cell–redirecting bispecific fusion …

[HTML][HTML] In situ forming mesoporous polydopamine nanocomposite thermogel for combined chemo-photothermal therapy of intraocular cancer

C Tao, Y Huang, J Chen, Q Peng, K Nan… - Colloid and Interface …, 2023 - Elsevier
Intraocular cancers such as retinoblastoma and uveal melanoma will induce severe vision
loss or even death. Herein, a versatile nanocomposite thermogel based on hexanoyl glycol …