[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
Considerations for polymers used in ocular drug delivery
MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …
been seen in the most common causes including glaucoma, age-related macular …
Gel/hydrogel‐based in situ biomaterial platforms for cancer postoperative treatment and recovery
Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …
perioperative treatment especially the postoperative adjuvant anticancer strategies play …
Nano-based formulations of curcumin: Elucidating the potential benefits and future prospects in skin cancer
C Ratan, AM Arian, R Rajendran… - Biomedical …, 2023 - iopscience.iop.org
Skin cancer refers to any malignant lesions that occur in the skin and are observed
predominantly in populations of European descent. Conventional treatment modalities such …
predominantly in populations of European descent. Conventional treatment modalities such …
Hyaluronic acid-based nanoparticles to deliver drugs to the ocular posterior segment
H Jiang, Z Xu - Drug Delivery, 2023 - Taylor & Francis
Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …
related macular degeneration usually result in progressive and irreversible vision loss …
Optimization of an injectable hydrogel depot system for the controlled release of retinal-targeted hybrid nanoparticles
A drawback in the development of treatments that can reach the retina is the presence of
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …
Curcumin doped zeolitic imidazolate framework nanoplatforms as multifunctional nanocarriers for tumor chemo/immunotherapy
J Liu, S Liu, Y Wu, X Xu, Q Li, M Yang, A Gong… - Biomaterials …, 2022 - pubs.rsc.org
Curcumin as a hydrophobic polyphenol has great potential for tumor therapy, yet its rapid
degradation and hydrophobicity severely impair its therapeutic effect in the clinic. Herein, we …
degradation and hydrophobicity severely impair its therapeutic effect in the clinic. Herein, we …
[HTML][HTML] In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma
Y Liu, W Ma, P Zhou, Q Wen, Q Wen, Y Lu… - Biomedicine & …, 2023 - Elsevier
Chemotherapy is one of the main therapeutic strategies for the treatment of malignant
melanoma. Conventional chemotherapeutic agents often lack targeting abilities, and efficacy …
melanoma. Conventional chemotherapeutic agents often lack targeting abilities, and efficacy …
From molecular biology to novel immunotherapies and nanomedicine in uveal melanoma
KJ Synoradzki, N Paduszyńska, M Solnik, MD Toro… - Current …, 2024 - mdpi.com
Molecular biology studies of uveal melanoma have resulted in the development of novel
immunotherapy approaches including tebentafusp—a T cell–redirecting bispecific fusion …
immunotherapy approaches including tebentafusp—a T cell–redirecting bispecific fusion …
[HTML][HTML] In situ forming mesoporous polydopamine nanocomposite thermogel for combined chemo-photothermal therapy of intraocular cancer
C Tao, Y Huang, J Chen, Q Peng, K Nan… - Colloid and Interface …, 2023 - Elsevier
Intraocular cancers such as retinoblastoma and uveal melanoma will induce severe vision
loss or even death. Herein, a versatile nanocomposite thermogel based on hexanoyl glycol …
loss or even death. Herein, a versatile nanocomposite thermogel based on hexanoyl glycol …