The oncogenic lysophosphatidylinositol (LPI)/GPR55 signaling

A Calvillo-Robledo, RD Cervantes-Villagrana… - Life sciences, 2022 - Elsevier
GPR55 is a class A orphan G protein-coupled receptor that has drawn important therapeutic
attention in the last decade because of its role in pathophysiological processes including …

Lysophosphatidylglucoside is a GPR55-mediated chemotactic molecule for human monocytes and macrophages

X Li, K Hanafusa, M Kage, N Yokoyama… - Biochemical and …, 2021 - Elsevier
Neutrophils undergo spontaneous apoptosis within 24–48 h after leaving bone marrow.
Apoptotic neutrophils are subsequently phagocytosed and cleared by macrophages …

Protecting-group-free glycosylation of phosphatidic acid in aqueous media

K Kano, N Ishii, A Miyagawa, H Takeda… - Organic & …, 2023 - pubs.rsc.org
The glycosylation of unprotected carbohydrates has emerged as an area of significant
interest because it obviates the need for long reaction sequences involving protecting-group …

Stereocontrolled Synthesis of Lyso‐phosphatidyl β‐D‐Glucoside

K Kano, N Ishii, Y Hirabayashi, H Kamiguchi… - …, 2021 - Wiley Online Library
Lyso‐phosphatidyl β‐D‐glucoside (lysoPtdGlc) is during embryonic development a neurite
growth cone guidance cue associated with G‐protein coupled receptor 55, and has been …

Chemical synthesis of phosphatidylglucoside

K Kano, N Ishii, P Greimel, I Matsuo - Glycolipids: methods and protocols, 2023 - Springer
stearoyl (18: 0)-2-arachidoyl (20: 0)-sn-glycero-3-phospho-ß-d-glucoside (
Phosphatidylglucoside or PtdGlc) was synthesized by direct coupling of d-glucose with the …