Arsenic and human health: genotoxicity, epigenomic effects, and cancer signaling

M Ozturk, M Metin, V Altay, RA Bhat, M Ejaz… - … Trace Element Research, 2022 - Springer
Arsenic is a well-known element because of its toxicity. Humans as well as plants and
animals are negatively affected by its exposure. Some countries suffer from high levels of …

Arsenic-induced changes in miRNA expression in cancer and other diseases

APF Cardoso, KT Udoh, JC States - Toxicology and applied pharmacology, 2020 - Elsevier
Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …

Effects of Aerobic Training and Curcumin Supplementation on Cardiomyocyte Apoptosis and MiRNAs Expression in Rats Exposed to Arsenic

A Majidi, R Poozesh Jadidi, MAR Nourazar… - Sport …, 2020 - spj.ssrc.ac.ir
The aim of this study was to investigate the effects of HIIT and curcumin supplementation on
cardiac tissue caspase 3 content and also expression of miR-1 and miR-133 in rats exposed …

Salvianolic acid A attenuates arsenic-induced ferroptosis and kidney injury via HIF-2α/DUOX1/GPX4 and iron homeostasis

D Yang, X Xia, S Xi - Science of The Total Environment, 2024 - Elsevier
Arsenic (As) is a prevalent pollutant in the environment and causes a high frequency of
kidney disease in areas of high arsenic contamination, but its pathogenic mechanisms have …

Prophylactic treatment with MSC-derived exosomes attenuates traumatic acute lung injury in rats

QC Li, Y Liang, ZB Su - American Journal of Physiology …, 2019 - journals.physiology.org
The mesenchymal stem cell (MSC) is a potential strategy in the pretreatment of traumatic
acute lung injury (ALI), a disease that causes inflammation and oxidative stress. This study …

Arsenic-induced epigenetic changes in cancer development

WN Saintilnord, Y Fondufe-Mittendorf - Seminars in cancer biology, 2021 - Elsevier
Arsenic is a ubiquitous metalloid whose high levels of toxicity pose major health concerns to
millions of people worldwide by increasing susceptibility to various cancers and non-cancer …

Epigenetic dysregulations in arsenic-induced carcinogenesis

R Islam, L Zhao, Y Wang, G Lu-Yao, LZ Liu - Cancers, 2022 - mdpi.com
Simple Summary Arsenic is a chemical element that is toxic, and long-term exposure to it
causes cancers such as lung, skin, liver, and bladder cancers. Over 150 million people …

Arsenic exposure, diabetes-related genes and diabetes prevalence in a general population from Spain

M Grau-Perez, A Navas-Acien, I Galan-Chilet… - Environmental …, 2018 - Elsevier
Inorganic arsenic exposure may be associated with diabetes, but the evidence at low-
moderate levels is not sufficient. Polymorphisms in diabetes-related genes have been …

Arsenic and cancer: Evidence and mechanisms

RM Speer, X Zhou, LB Volk, KJ Liu… - Advances in Pharmacology, 2023 - Elsevier
Arsenic is a potent carcinogen and poses a significant health concern worldwide. Exposure
occurs through ingestion of drinking water and contaminated foods and through inhalation …

Arsenic-induced carcinogenesis: the impact of miRNA dysregulation

APF Cardoso, L Al-Eryani, JC States - Toxicological Sciences, 2018 - academic.oup.com
Arsenic is a toxic metalloid widely present in the earth's crust, and is a proven human
carcinogen. Chronic arsenic exposure mainly through drinking water causes skin, lung, and …