Head and neck cancer (HNC) is an ascending and agressive disease. The search for new
molecular markers is emerging to solve difficulties in diagnosis, risk management, prognosis …

Many anticancer strategies rely on the promotion of apoptosis in cancer cells as a means to
shrink tumors. Crucial for apoptotic function are executioner caspases, most notably …

Background: Survivin is an inhibitor of apoptosis protein (IAP), encoded by the Baculoviral
IAP Repeat Containing 5 (BIRC5) gene located on q arm (25.3) on chromosome 17. It is …

Arctigenin, a dibenzylbutyrolactone lignan, enhances cisplatin‐mediated cell apoptosis in
cancer cells. Here, we sought to investigate the effects of arctigenin on cisplatin‐treated non …

Survivin is an anti-apoptotic gene that is overexpressed in most human tumors. RNA
interference using short interfering RNA (siRNA) can be used to specifically inhibit survivin …

In 1997 for the first time, survivin was described by Amborsini et al. as an anti-apoptotic
protein. Subsequent studies revealed that survivin is a multifunctional protein that plays …

In this study, the anti-tumor activity of ilimaquinone (IQ), a sesquiterpene quinone isolated
from marine sponge Halichondria sp., in oral squamous cell carcinoma (OSCC) cells, was …

The present study aimed to investigate the impact of survivin and caspase‑3 on apoptosis
and angiogenesis in oral cancer. A total of 16 oral leukoplakia cases accompanied by low …

BACKGROUND Circulating tumor cells (CTCs) and survivin are indicators for tumor stage
and metastasis, as well as epitheliomesenchymal transition, in various cancers, including …

Objectives We have previously reported inactivation of p53 in 46% of Indian patients with
oral cancer. Survivin, a p53 target gene and an inhibitor of apoptosis protein (IAP), is …