Template-assembled synthetic G-quartets (TASQs): multiTASQing molecular tools for investigating DNA and RNA G-quadruplex biology

D Monchaud - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Biomimetics is defined as a “practice of making technological design that copies
natural processes”, with the idea that “nature has already solved the challenges we are …

Nucleic acid detection using G-quadruplex amplification methodologies

BT Roembke, S Nakayama, HO Sintim - Methods, 2013 - Elsevier
In the last decade, there has been an explosion in the use of G-quadruplex labels to detect
various analytes, including DNA/RNA, proteins, metals and other metabolites. In this review …

A model of smart G-quadruplex ligand

R Haudecoeur, L Stefan, F Denat… - Journal of the American …, 2013 - ACS Publications
An unprecedented strategy to control the quadruplex-vs duplex-DNA selectivity of a ligand is
reported. We designed a compound whose structure can rearrange when it interacts with a …

Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid

V Basavalingappa, S Bera, B Xue, I Azuri… - Nature …, 2019 - nature.com
The variety and complexity of DNA-based structures make them attractive candidates for
nanotechnology, yet insufficient stability and mechanical rigidity, compared to polyamide …

Interaction of polycationic Ni (II)-salophen complexes with G-quadruplex DNA

L Lecarme, E Prado, A De Rache… - Inorganic …, 2014 - ACS Publications
A series of nine Ni (II) salophen complexes involving one, two, or three alkyl-imidazolium
side-chains was prepared. The lengths of the side-chains were varied from one to three …

Assessing the differential affinity of small molecules for noncanonical DNA structures

L Stefan, B Bertrand, P Richard, P Le Gendre… - …, 2012 - Wiley Online Library
The targeting of higher‐order DNA structures has been thoroughly developed with G‐
quadruplex DNA but not with other structures like branched DNA (also known as DNA …

Biomimetic, smart, and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging

FR Sperti, T Charbonnier, P Lejault, J Zell… - ACS Chemical …, 2021 - ACS Publications
G-quadruplexes (G4s) continue to gather wide attention in the field of chemical biology as
their prevalence in the human genome and transcriptome strongly suggests that they play …

[HTML][HTML] RM1 semiempirical model: chemistry, pharmaceutical research, molecular biology and materials science

NBD Lima, GB Rocha, RO Freire… - Journal of the Brazilian …, 2019 - SciELO Brasil
In this review, we show improvements to the semiempirical quantum chemical method RM1
and present a wide range of its applications as reported by researchers of various areas …

Multitasking Water‐Soluble Synthetic G‐Quartets: From Preferential RNA–Quadruplex Interaction to Biocatalytic Activity

R Haudecoeur, L Stefan… - Chemistry–A European …, 2013 - Wiley Online Library
Natural G‐quartets, a cyclic and coplanar array of four guanine residues held together
through a Watson–Crick/Hoogsteen hydrogen‐bond network, have received recently much …

A Fluorescent Guanosine Dinucleoside as a Selective Switch‐On Sensor for c‐myc G‐Quadruplex DNA with Potent Anticancer Activities

YP Kumar, S Bhowmik, RN Das, I Bessi… - … A European Journal, 2013 - Wiley Online Library
Development of fluorescent chemical probes that can recognize biomacromolecules with
high specificity and interfere with cellular processes is an emerging trend in chemical …