Template-assembled synthetic G-quartets (TASQs): multiTASQing molecular tools for investigating DNA and RNA G-quadruplex biology
D Monchaud - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Biomimetics is defined as a “practice of making technological design that copies
natural processes”, with the idea that “nature has already solved the challenges we are …
natural processes”, with the idea that “nature has already solved the challenges we are …
Nucleic acid detection using G-quadruplex amplification methodologies
BT Roembke, S Nakayama, HO Sintim - Methods, 2013 - Elsevier
In the last decade, there has been an explosion in the use of G-quadruplex labels to detect
various analytes, including DNA/RNA, proteins, metals and other metabolites. In this review …
various analytes, including DNA/RNA, proteins, metals and other metabolites. In this review …
A model of smart G-quadruplex ligand
R Haudecoeur, L Stefan, F Denat… - Journal of the American …, 2013 - ACS Publications
An unprecedented strategy to control the quadruplex-vs duplex-DNA selectivity of a ligand is
reported. We designed a compound whose structure can rearrange when it interacts with a …
reported. We designed a compound whose structure can rearrange when it interacts with a …
Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid
The variety and complexity of DNA-based structures make them attractive candidates for
nanotechnology, yet insufficient stability and mechanical rigidity, compared to polyamide …
nanotechnology, yet insufficient stability and mechanical rigidity, compared to polyamide …
Interaction of polycationic Ni (II)-salophen complexes with G-quadruplex DNA
L Lecarme, E Prado, A De Rache… - Inorganic …, 2014 - ACS Publications
A series of nine Ni (II) salophen complexes involving one, two, or three alkyl-imidazolium
side-chains was prepared. The lengths of the side-chains were varied from one to three …
side-chains was prepared. The lengths of the side-chains were varied from one to three …
Assessing the differential affinity of small molecules for noncanonical DNA structures
L Stefan, B Bertrand, P Richard, P Le Gendre… - …, 2012 - Wiley Online Library
The targeting of higher‐order DNA structures has been thoroughly developed with G‐
quadruplex DNA but not with other structures like branched DNA (also known as DNA …
quadruplex DNA but not with other structures like branched DNA (also known as DNA …
Biomimetic, smart, and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging
FR Sperti, T Charbonnier, P Lejault, J Zell… - ACS Chemical …, 2021 - ACS Publications
G-quadruplexes (G4s) continue to gather wide attention in the field of chemical biology as
their prevalence in the human genome and transcriptome strongly suggests that they play …
their prevalence in the human genome and transcriptome strongly suggests that they play …
[HTML][HTML] RM1 semiempirical model: chemistry, pharmaceutical research, molecular biology and materials science
In this review, we show improvements to the semiempirical quantum chemical method RM1
and present a wide range of its applications as reported by researchers of various areas …
and present a wide range of its applications as reported by researchers of various areas …
Multitasking Water‐Soluble Synthetic G‐Quartets: From Preferential RNA–Quadruplex Interaction to Biocatalytic Activity
R Haudecoeur, L Stefan… - Chemistry–A European …, 2013 - Wiley Online Library
Natural G‐quartets, a cyclic and coplanar array of four guanine residues held together
through a Watson–Crick/Hoogsteen hydrogen‐bond network, have received recently much …
through a Watson–Crick/Hoogsteen hydrogen‐bond network, have received recently much …
A Fluorescent Guanosine Dinucleoside as a Selective Switch‐On Sensor for c‐myc G‐Quadruplex DNA with Potent Anticancer Activities
Development of fluorescent chemical probes that can recognize biomacromolecules with
high specificity and interfere with cellular processes is an emerging trend in chemical …
high specificity and interfere with cellular processes is an emerging trend in chemical …