PI3K/Akt/mTOR signaling pathway in cancer stem cells
M Ebrahimi, E Nourbakhsh, AZ Hazara… - … -Research and Practice, 2022 - Elsevier
Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …
The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: When the dialogue replaces the monologue
M Di Donato, P Giovannelli, A Migliaccio, G Castoria - Cell & Bioscience, 2023 - Springer
Prostate cancer (PC) represents the most diagnosed and the second most lethal cancer in
men worldwide. Its development and progression occur in concert with alterations in the …
men worldwide. Its development and progression occur in concert with alterations in the …
IL‐6 Signaling Link between Inflammatory Tumor Microenvironment and Prostatic Tumorigenesis
CV Ene, I Nicolae, B Geavlete… - Analytical Cellular …, 2022 - Wiley Online Library
Benign prostatic hyperplasia and prostate cancer are tumoral pathologies characterized by
the overexpression of inflammatory processes. The exploration of tumor microenvironment …
the overexpression of inflammatory processes. The exploration of tumor microenvironment …
Epithelial-to-mesenchymal transition-related markers in prostate cancer: From bench to bedside
S Gogola, M Rejzer, HF Bahmad, W Abou-Kheir… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is the second most frequent type of cancer in men
worldwide. Treatment options for early-stage PCa include external beam radiation therapy …
worldwide. Treatment options for early-stage PCa include external beam radiation therapy …
FOXA1 regulates alternative splicing in prostate cancer
Dysregulation of alternative splicing in prostate cancer is linked to transcriptional programs
activated by AR, ERG, FOXA1, and MYC. Here, we show that FOXA1 functions as the …
activated by AR, ERG, FOXA1, and MYC. Here, we show that FOXA1 functions as the …
Combinatorial approaches of nanotherapeutics for inflammatory pathway targeted therapy of prostate cancer
Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …
Angioprevention of urologic cancers by plant-derived foods
M García-Caballero, JA Torres-Vargas, AD Marrero… - Pharmaceutics, 2022 - mdpi.com
The number of cancer cases worldwide keeps growing unstoppably, despite the undeniable
advances achieved by basic research and clinical practice. Urologic tumors, including some …
advances achieved by basic research and clinical practice. Urologic tumors, including some …
Precision intervention for prostate cancer: re-evaluating who is at risk
A Papachristodoulou, C Abate-Shen - Cancer letters, 2022 - Elsevier
The vast majority of new prostate cancer diagnoses are low-grade tumors that are monitored
by active surveillance rather than undergoing immediate treatment. However, a subset of …
by active surveillance rather than undergoing immediate treatment. However, a subset of …
A harmonized resource of integrated prostate cancer clinical,-omic, and signature features
Genomic and transcriptomic data have been generated across a wide range of prostate
cancer (PCa) study cohorts. These data can be used to better characterize the molecular …
cancer (PCa) study cohorts. These data can be used to better characterize the molecular …
Prognostic significance of pretreatment systemic immune-inflammation index in patients with prostate cancer: a meta-analysis
B Zhang, T Xu - World Journal of Surgical Oncology, 2023 - Springer
Background The SII (systemic immune-inflammation index) has been extensively reported to
have a prognostic value in prostate cancer (PCa), despite the unconformable results. The …
have a prognostic value in prostate cancer (PCa), despite the unconformable results. The …