Nanotechnology transition roadmap toward multifunctional stimuli-responsive face masks

A Zakrzewska, MA Haghighat Bayan… - … Applied Materials & …, 2022 - ACS Publications
In recent times, the use of personal protective equipment, such as face masks or respirators,
is becoming more and more critically important because of common pollution; furthermore …

Recent advances in targeted delivery of non-coding RNA-based therapeutics for atherosclerosis

X Li, H Qi, W Cui, Z Wang, X Fu, T Li, H Ma, Y Yang… - Molecular Therapy, 2022 - cell.com
Cardiovascular disease (CVD) has overtaken infectious illnesses as the leading cause of
mortality and disability worldwide. The pathology that underpins CVD is atherosclerosis …

siRNA delivery against myocardial ischemia reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes

Y Zhou, Q Liang, X Wu, S Duan, C Ge, H Ye… - Advanced …, 2023 - Wiley Online Library
Abstract siRNA‐mediated management of myocardial ischemia reperfusion (IR) injury is
greatly hampered by the inefficient myocardial enrichment and cardiomyocyte transfection …

Oral Delivery of siRNA Using Fluorinated, Small‐Sized Nanocapsules toward Anti‐Inflammation Treatment

Y Wei, X Li, J Lin, Y Zhou, J Yang, M Hou… - Advanced …, 2023 - Wiley Online Library
Oral delivery of small interfering RNA (siRNA) provides a promising paradigm for treating
diseases that require regular injections. However, the multiple gastrointestinal (GI) and …

Evolution of nanostructured skin patches towards multifunctional wearable platforms for biomedical applications

D Rybak, YC Su, Y Li, B Ding, X Lv, Z Li, YC Yeh… - Nanoscale, 2023 - pubs.rsc.org
Recent advances in the field of skin patches have promoted the development of wearable
and implantable bioelectronics for long-term, continuous healthcare management and …

Stabilizing RNA nanovaccines with transformable hyaluronan dynamic hydrogel for durable cancer immunotherapy

F Jia, W Huang, Y Yin, Y Jiang, Q Yang… - Advanced Functional …, 2023 - Wiley Online Library
Massage RNA (mRNA) vaccines represent a new strategy for advanced cancer
immunotherapy. To protect mRNA from degradation and deliver to targeted cells, lipid …

Advances in siRNA delivery approaches in cancer therapy: challenges and opportunities

H Isazadeh, F Oruji, S Shabani, J Behroozi… - Molecular Biology …, 2023 - Springer
Advancements in the clinical applications of small interfering RNA (siRNA) in cancer therapy
have opened up new possibilities for precision medicine. siRNAs, as powerful genetic tools …

Platelet pharmacytes for the hierarchical amplification of antitumor immunity in response to self‐generated immune signals

J Yan, X Liu, F Wu, C Ge, H Ye, X Chen… - Advanced …, 2022 - Wiley Online Library
Systemic immunosuppression mediated by tumor‐derived exosomes is an important cause
for the resistance of immune checkpoint blockade (ICB) therapy. Herein, self‐adaptive …

Endothelial cell-targeting, ROS-ultrasensitive drug/siRNA co-delivery nanocomplexes mitigate early-stage neutrophil recruitment for the anti-inflammatory treatment of …

M Hou, X Wu, Z Zhao, Q Deng, Y Chen, L Yin - Acta Biomaterialia, 2022 - Elsevier
Neutrophils serve as a key contributor to the pathophysiology of myocardial ischemia
reperfusion injury (MIRI), because the unregulated activation and infiltration of neutrophils …

[HTML][HTML] Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion …

Y Wang, M Hou, S Duan, Z Zhao, X Wu, Y Chen, L Yin - Bioactive materials, 2022 - Elsevier
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after
infarction and thrombolytic therapy, and it is closely related to the free radical explosion and …