Resistance to chemotherapy substantially hinders successful glioblastoma (GBM) treatment,
contributing to an almost 100% mortality rate. Resistance to the frontline chemotherapy …

To investigate the role and potential mechanism of serine/threonine kinase 36 (STK36) in
docetaxel resistance-prostate cancer (PCa). The expression of STK36 in PCa and the …

Abstract Herpes simplex virus-1 (HSV-1) is a double-stranded DNA virus that causes life-
long infections. HSV-1 infections may lead to herpetic stromal keratitis that may advance to …

Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, with
nearly 100% of patients ultimately succumbing to the disease. Median patient survival is 15 …

This paper outlines a treatment protocol to run alongside of standard current treatment of
glioblastoma-resection, temozolomide and radiation. The epithelial to mesenchymal …

The first‐line chemotherapy treatment for Glioblastoma (GBM)‐the most aggressive and
frequent brain tumor‐is temozolomide (TMZ). The Sonic hedgehog (SHH) pathway is …

High-grade gliomas (HGG) have high malignancy, high heterogeneity, and a poor
prognosis. Tumor purity is an intrinsic feature of the HGG microenvironment and an …

World Health Organization grade IV diffuse gliomas, known as glioblastomas, are the most
common malignant brain tumors, and they show poor prognosis. Multimodal treatment of …

Background Glioblastoma (GBM) is the most common primary malignant brain tumor in
adults with a poor prognosis. DEPDC1B (DEP domain-containing protein 1B) has been …

The size of neural stem cell (NSC) pool at birth determines the starting point of adult
neurogenesis. Aberrant neurogenesis is associated with major mental illness, in which …