[HTML][HTML] Emergence and rapid dissemination of highly resistant NDM-14-producing Klebsiella pneumoniae ST147, France, 2022

C Emeraud, A Mahamat, AB Jousset… - …, 2023 - eurosurveillance.org
Background Since 2021, an emergence of New Delhi metallo-β-lactamase (NDM)-14-
producing Klebsiella pneumoniae has been identified in France. This variant with increased …

Nationwide molecular epidemiology of carbapenemase-producing Citrobacter spp. in France in 2019 and 2020

L Biez, RA Bonnin, C Emeraud, A Birer, AB Jousset… - Msphere, 2023 - Am Soc Microbiol
Carbapenemase-producing Enterobacterales have emerged in the last decades as one of
the main threats in modern medicine. Enterobacter is a genus increasingly recognized as a …

An antiplasmid system drives antibiotic resistance gene integration in carbapenemase-producing Escherichia coli lineages

PD Zongo, N Cabanel, G Royer, F Depardieu… - Nature …, 2024 - nature.com
Plasmids carrying antibiotic resistance genes (ARG) are the main mechanism of resistance
dissemination in Enterobacterales. However, the fitness-resistance trade-off may result in …

The Use of Long-Read Sequencing Technologies in Infection Control: Horizontal Transfer of a blaCTX-M-27 Containing lncFII Plasmid in a Patient Screening …

V van Almsick, F Schuler, A Mellmann, V Schwierzeck - Microorganisms, 2022 - mdpi.com
Plasmid transfer is one important mechanism how antimicrobial resistance can spread
between different species, contributing to the rise of multidrug resistant bacteria (MDRB) …

[HTML][HTML] Genome stability during serial subculturing in hyperepidemic multidrug-resistant Klebsiella pneumoniae and Escherichia coli

AI Moser, EI Campos-Madueno, V Perreten… - Journal of global …, 2022 - Elsevier
Objectives Core-genome single nucleotide variant (cgSNV) analysis represents a powerful
tool for epidemiological investigations of multidrug-resistant (MDR) bacteria. However …

Plasmid genomic epidemiology of carbapenem-hydrolysing class D β-lactamase (CDHL)-producing Enterobacterales in Canada, 2010−2021

N Lerminiaux, R Mitchell, K Katz… - Microbial …, 2024 - microbiologyresearch.org
Carbapenems are last-resort antibiotics for treatment of infections caused by multidrug-
resistant Enterobacterales, but carbapenem resistance is a rising global threat due to the …

Risk factors and molecular epidemiology of intestinal colonization by carbapenem-resistant Gram-negative bacteria in patients with hematological diseases: a …

H Hu, Y Wang, J Sun, Y Wang, J Zhou, Q Shi… - Microbiology …, 2024 - Am Soc Microbiol
Patients with hematological diseases are considered to be at high risk for intestinal
colonization by carbapenem-resistant Gram-negative bacteria (CR-GNB). However, the …

Molecular Typing of mcr-1 Escherichia Coli Isolates From Pigs and Farm Environment Based on fumC and fimH Alleles

GS Oliveira, SAM Lentz, PL Wink, AF Martins - Future Microbiology, 2023 - Taylor & Francis
Background: The dissemination of polymyxin resistance represents a significant threat to
public health. Materials & methods: Sequence-based typing was performed by 53 mcr-1 …

Elimination of blaKPC−2-mediated carbapenem resistance in Escherichia coli by CRISPR-Cas9 system

S Tao, H Chen, N Li, Y Fang, H Zhang, Y Xu, L Chen… - BMC microbiology, 2023 - Springer
Objective The purpose of this study is to re-sensitive bacteria to carbapenemases and
reduce the transmission of the bla KPC− 2 gene by curing the bla KPC− 2-harboring plasmid …

[HTML][HTML] Transmission of global clones of NDM-producing Enterobacterales and interspecies spread of IncX3 plasmid harbouring blaNDM-5 in Tokyo

S Harada, K Aoki, Y Nomura, Y Ohama… - Journal of Global …, 2024 - Elsevier
Objective The aim of this study is to characterise the molecular characteristics of NDM-
producing Enterobacterales, which have been on the increase in recent years in Japan …