Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
H5 influenza is considered a potential pandemic threat. Recently, H5 viruses belonging to
clade 2.3. 4.4 b have caused large outbreaks in avian and multiple nonhuman mammalian …
clade 2.3. 4.4 b have caused large outbreaks in avian and multiple nonhuman mammalian …
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
In 2024, several human infections with highly pathogenic clade 2.3. 4.4 b bovine influenza
H5N1 viruses in the United States raised concerns about their capability for bovine-to …
H5N1 viruses in the United States raised concerns about their capability for bovine-to …
Bovine H5N1 influenza virus binds poorly to human-type sialic acid receptors
Clade 2.3. 4.4 b highly pathogenic H5N1 avian influenza (HPAI) viruses started circulating
widely in lactating dairy cattle in the United States at the end of 2023. Avian influenza …
widely in lactating dairy cattle in the United States at the end of 2023. Avian influenza …
Structural and Functional Insights into the Evolution of SARS-CoV-2 KP. 3.1. 1 Spike Protein
The JN. 1-sublineage KP. 3.1. 1 recently emerged as the globally prevalent SARS-CoV-2
variant, demonstrating increased infectivity and antibody escape. We investigated how …
variant, demonstrating increased infectivity and antibody escape. We investigated how …
Epistasis in the receptor binding domain of contemporary H3N2 viruses that reverted to bind sialylated diLacNAc repeats
R Liang, F Peccati, NLD Ponse, E Uslu, GJ Boons… - bioRxiv, 2024 - biorxiv.org
Since the introduction of H3N2 influenza A viruses in the human population, these viruses
have continuously evolved to escape human immunity, with mutations occurring in and …
have continuously evolved to escape human immunity, with mutations occurring in and …