Melatonin is an old and ubiquitous molecule in nature showing multiple mechanisms of
action and functions in practically every living organism. In mammals, pineal melatonin …

Obesity and its medical complications represent a significant problem throughout the world.
In recent decades, mechanisms underlying the progression of obesity have been intensively …

Os avanços da pesquisa sobre as propriedades metabólicas do tecido adiposo e as
recentes descobertas sobre sua capacidade em produzir hormônios atuantes em processos …

Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus
(SCN) and peripheral circadian oscillators regulate physiology and metabolism to set …

Leptin and melatonin play an important role in the regulation of body mass and energy
balance. Both hormones show a circadian rhythm, with increasing values at night. In …

The aim of this work was to investigate the effect of the in vitro circadian‐like exposure to
melatonin [in the presence or absence of insulin (Ins)] on the metabolism and clock gene …

Melatonin is synthesized in the pineal gland, but elicits a wide range of physiological
responses in peripheral target tissues. Recent advances suggest that melatonin controls …

Considering that melatonin has been implicated in body weight control, this work
investigated whether this effect involves the regulation of adipogenesis. 3T3‐L1 …

Accumulating evidence indicates that various biological and neuroendocrine circadian
rhythms may be disrupted in cardiovascular and metabolic disorders. These circadian …

Melatonin, a pivotal photoperiodic signal transducer, may work as a brown-fat inducer that
regulates energy balance. Our study aimed to investigate the effects of melatonin treatment …