The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy
critical to neuronal function while simultaneously excluding neurotoxic substances from the …

Ischemic stroke, a major cause of mortality in the United States, often contributes to
disruption of the blood-brain barrier (BBB). The BBB along with its supportive cells …

The gut microbiota and its short chain fatty acid (SCFA) metabolites have been established
to play an important protective role against neurodegenerative diseases. Our previous study …

Blood–brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional
proteins and increased permeability, is a crucial pathophysiological feature of acute …

Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …

Fatty acids are good energy sources (9 kcal per gram) that aerobic tissues can use except
for the brain (glucose is an alternative source). Apart from the energy source, fatty acids are …

The incidence and mortality of strokes have increased over the past three decades in China.
Ischemic strokes can cause a sequence of detrimental events in patients, including …

Stroke is the second cause of death and more importantly first cause of disability in people
over 40 years of age. Current therapeutic management of ischemic stroke does not provide …

Salidroside (Sal) is a bioactive extract principally from traditional herbal medicine such as
Rhodiola rosea L., which has been commonly used for hundreds of years in Asia countries …