Liquid chromatography-mass spectrometry (LC-MS) is now a routine technique with the
development of electrospray ionisation (ESI) providing a simple and robust interface. It can …

Liquid chromatography-mass spectrometry (LC-MS) is one of the most prominent analytical
techniques, due to its inherent selectivity and sensitivity. In LC-MS, chemical derivatizations …

Objective: The objective of the study was to evaluate the current state of clinical assays for
total and free testosterone. Participants: The five participants were appointed by the Council …

The challenge of chemical exposomics in human plasma is the 1000-fold concentration gap
between endogenous substances and environmental pollutants. Phospholipids are the …

Context: Reference ranges are essential for partitioning testosterone levels into low or
normal and making the diagnosis of androgen deficiency. We established reference ranges …

Background: Psychosocial stress is a significant public health problem inducing
consequences for quality of life. Results about the use of dehydroepiandrosterone (DHEA) …

Measuring serum androgen levels in women has been challenging due to limitations in
method accuracy, precision sensitivity and specificity at low hormone levels. The clinical …

Background: Measurement of serum androgens is important in adult, geriatric, pediatric
endocrinology, and oncology patients. We developed a liquid chromatography—tandem …

Endocrine disease frequently interrupts sexual function, and sexual dysfunction may signal
serious endocrine disease. Diabetic autonomic neuropathy and endothelial dysfunction …

During the past decade, tandem mass spectrometry hyphenated to liquid chromatography
separation systems (HPLC–MS/MS) has developed to an important technology in clinical …