Sustained detection of type 2 poliovirus in London sewage between February and July, 2022, by enhanced environmental surveillance

D Klapsa, T Wilton, A Zealand, E Bujaki, E Saxentoff… - The Lancet, 2022 - thelancet.com
Background The international spread of poliovirus exposes all countries to the risk of
outbreaks and is designated a Public Health Emergency of International Concern by WHO …

[PDF][PDF] Advancing pathogen genomics in resource-limited settings

PM Pronyk, R de Alwis, R Rockett, K Basile… - Cell Genomics, 2023 - cell.com
Genomic sequencing has emerged as a powerful tool to enhance early pathogen detection
and characterization with implications for public health and clinical decision making …

The challenges of informative wastewater sampling for SARS-CoV-2 must be met: lessons from polio eradication

KM O'Reilly, DJ Allen, P Fine, H Asghar - The Lancet Microbe, 2020 - thelancet.com
Since the emergence and spread of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which has caused the COVID-19 pandemic, many countries have rapidly …

Detection of Enterovirus D68 in Wastewater Samples from the UK between July and November 2021

A Tedcastle, T Wilton, E Pegg, D Klapsa, E Bujaki… - Viruses, 2022 - mdpi.com
Infection with enterovirus D68 (EV-D68) has been linked with severe neurological disease
such as acute flaccid myelitis (AFM) in recent years. However, active surveillance for EV …

The Last Mile in Polio Eradication: Program Challenges and Perseverance

R Lopez Cavestany, M Eisenhawer, OM Diop, H Verma… - Pathogens, 2024 - mdpi.com
As the Global Polio Eradication Initiative (GPEI) strategizes towards the final steps of
eradication, routine immunization schedules evolve, and high-quality vaccination …

Sensitive poliovirus detection using nested PCR and nanopore sequencing: a prospective validation study

AG Shaw, TK Mampuela, EL Lofiko, C Pratt… - Nature …, 2023 - nature.com
Timely detection of outbreaks is needed for poliovirus eradication, but gold standard
detection in the Democratic Republic of the Congo takes 30 days (median). Direct molecular …

Defining the methodological approach for wastewater-based epidemiological studies—Surveillance​ of SARS-CoV-2

H Kopperi, A Tharak, M Hemalatha, U Kiran… - … Technology & Innovation, 2021 - Elsevier
Abstract Since COVID-19 outbreak, wastewater-based epidemiology (WBE) studies as
surveillance system is becoming an emerging interest due to its functional advantage as a …

Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children

A Singanayagam, D Klapsa, S Burton-Fanning… - Nature …, 2023 - nature.com
Increasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries
previously declared polio free, is a public health emergency of international concern …

Enterovirus Surveillance (EVSurv) in Germany

K Keeren, S Böttcher, LaNED, S Diedrich - Microorganisms, 2021 - mdpi.com
The major aim of the enterovirus surveillance (EVSurv) in Germany is to prove the absence
of poliovirus circulation in the framework of the Global Polio Eradication Program (GPEI) …

Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data

SG Sutcliffe, SA Kraemer, I Ellmen… - Microbial …, 2024 - microbiologyresearch.org
Wastewater-based surveillance (WBS) is an important epidemiological and public health
tool for tracking pathogens across the scale of a building, neighbourhood, city, or region …