Twenty years of Mediator complex structural studies
Mediator is a large multiprotein complex conserved in all eukaryotes that plays an essential
role in transcriptional regulation. Mediator comprises 25 subunits in yeast and 30 subunits in …
role in transcriptional regulation. Mediator comprises 25 subunits in yeast and 30 subunits in …
The Mediator complex in plants: structure, phylogeny, and expression profiling of representative genes in a dicot (Arabidopsis) and a monocot (rice) during …
Abstract The Mediator (Med) complex relays regulatory information from DNA-bound
transcription factors to the RNA polymerase II in eukaryotes. This macromolecular unit is …
transcription factors to the RNA polymerase II in eukaryotes. This macromolecular unit is …
Gene-specific transcription activation via long-range allosteric shape-shifting
CJ Tsai, R Nussinov - Biochemical Journal, 2011 - portlandpress.com
How is specificity transmitted over long distances at the molecular level? REs (regulatory
elements) are often far from transcription start sites. In the present review we discuss …
elements) are often far from transcription start sites. In the present review we discuss …
MEDIATOR18 and MEDIATOR20 confer susceptibility to Fusarium oxysporum in Arabidopsis thaliana
The conserved protein complex known as Mediator conveys transcriptional signals by acting
as an intermediary between transcription factors and RNA polymerase II. As a result …
as an intermediary between transcription factors and RNA polymerase II. As a result …
The Mediator complex and the role of protein-protein interactions in the gene regulation machinery
E Sierecki - Seminars in Cell & Developmental Biology, 2020 - Elsevier
At the core of gene regulation, a complex network of dynamic interactions between proteins,
DNA and RNA has to be integrated in order to generate a binary biological output. Large …
DNA and RNA has to be integrated in order to generate a binary biological output. Large …
PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα‐Interacting Cofactor Complex
SR Pyper, N Viswakarma, Y Jia, YJ Zhu… - PPAR …, 2010 - Wiley Online Library
The peroxisome proliferator‐activated receptor‐α (PPARα) plays a key role in lipid
metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the …
metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the …
[PDF][PDF] Investigation of virus-induced defence modulations during plant-virus interactions
LS Pretorius - 2018 - core.ac.uk
Turnip mosaic virus (TuMV) is a single stranded RNA (sRNAs) virus belonging to the genus
Potyvirus. Turnip mosaic virus has a wide host range including several important crop …
Potyvirus. Turnip mosaic virus has a wide host range including several important crop …
[图书][B] The role of Arabidopsis mediator complex in plant defense
CM Schluttenhofer - 2011 - search.proquest.com
Plant diseases cause significant crop losses world-wide. Understanding the mechanisms of
plant defense is imperative to designing better disease control strategies. Previously, our lab …
plant defense is imperative to designing better disease control strategies. Previously, our lab …
PRIC295, a Nuclear Receptor Coactivator, Identified from PPAR𝛼-Interacting Cofactor Complex
SR Pyper, N Viswakarma, Y Jia, YJ Zhu, JD Fondell… - 2010 - agris.fao.org
The peroxisome proliferator-activated receptor-𝛼 (PPAR𝛼) plays a key role in lipid
metabolism and energy combustion. Chronic activation of PPAR𝛼 in rodents leads to the …
metabolism and energy combustion. Chronic activation of PPAR𝛼 in rodents leads to the …
[PDF][PDF] Research Article PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
SR Pyper, N Viswakarma, Y Jia, YJ Zhu, JD Fondell… - 2010 - academia.edu
The peroxisome proliferator-activated receptor-α (PPARα) plays a key role in lipid
metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the …
metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the …