The brain continuously adapts its processing machinery to behavioural demands. To
achieve this, it rapidly modulates the operating mode of cortical circuits, controlling the way …

Functional magnetic resonance imaging (fMRI) has allowed the noninvasive study of task-
based and resting-state brain dynamics in humans by inferring neural activity from blood …

Spontaneous activity plays an important role in the function of neural circuits. Although many
similarities between spontaneous and sensory-evoked neocortical activity have been …

The response of neurons in sensory cortex to repeated stimulus presentations is highly
variable. To investigate the nature of this variability, we compared the spike activity of …

Cognitive function relies on a dynamic, context-sensitive balance between functional
integration and segregation in the brain. Previous work has proposed that this balance is …

Even in the quietest of rooms, our senses are perpetually inundated by a barrage of sounds,
requiring the auditory system to adapt to a variety of listening conditions in order to extract …

In the idling brain, neuronal circuits transition between periods of sustained firing (UP state)
and quiescence (DOWN state), a pattern the mechanisms of which remain unclear. Here we …

Behavior relies on the distributed and coordinated activity of neural populations. Population
activity can be measured using multi-neuron recordings and neuroimaging. Neural …

We studied how the posterior parietal cortex combines new information with ongoing activity
dynamics as mice accumulate evidence during a virtual navigation task. Using new methods …

During non-rapid eye movement (NREM) sleep, neuronal populations in the mammalian
forebrain alternate between periods of spiking and inactivity. Termed the slow oscillation in …