Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …

Chemotherapy is a critical treatment modality for cancer patients, but multidrug resistance
remains one of the major challenges in cancer therapy, creating an urgent need for the …

Abstract In this study, N-[3-(3-amino-1, 4-dioxo-1, 4-dihydronaphthalen-2-yl)-4-R-thiazol-2
(3H)-ylidene]-2, 6-difluorobenzamide derivatives as new 1, 4-naphthoquinone thiazole …

Objective: Benzofurans, fused pyrazole systems, and thiazole moieties are the most
important pharmacophores and intermediates for making drugs. The preparation and anti …

Cancer stands as one of the deadliest diseases, ranking second in terms of its global impact.
Despite the presence of numerous compelling theories concerning its origins, none have …

Curcumin, derived from the popular spice turmeric, is a pharmacologically active
polyphenol. Curcumin's therapeutic activity has been extensively studied in recent decades …

Several curcumin analogues (C01-C03) were prepared in green solvent (water-glycerol; 2: 1
v/v) with boric acid (10% mol solution in glycerol). All the compounds were characterized by …

The thiazole ring closure of thiosemicarbazones with α-bromo-4-substituted acetophenones
was carried out to generate aminothiazole analogues (A1–A16). Experimental methods …

Breast cancer stands as the leading cause of cancer‐related deaths among women globally,
but current therapy is restricted to the serious adverse effects and multidrug resistance …

Overseeing the diverse pharmacological traits of curcumin, a novel monocarbonyl based
curcumin derivative (1-(4-ethylbenzoyl)-3, 5-bis ((E)-4-methoxybenzylidene) piperidin-4 …