In vitro maturation (IVM) is emerging as a popular technology at the forefront of fertility
treatment and preservation. However, standard in vitro culture (IVC) conditions usually …

Calcium (Ca++) is one of the major signal molecules that regulate various aspects of cell
functions including cell cycle progression, arrest, and apoptosis in wide variety of cells. This …

The mammalian ovary is a metabolically active organ and generates a large amount of
reactive oxygen species (ROS) during final stages of folliculogenesis. ROS modulate …

Aim The mammalian ovary generates reactive oxygen species (ROS) on an extraordinary
scale; however, the role of ROS during meiotic cell cycle progression in follicular oocytes …

Oxidative stress initiates various degenerative diseases, and it is caused by excessive
reactive oxygen species (ROS) production. Oxidative stress is a key factor that causes …

In ovarian follicles, cumulus cells communicate with the oocyte through gap junction
intercellular communication (GJIC), to nurture the oocyte and control its meiosis arrest and …

The maximum number of germ cells is present during the fetal life in mammals. Follicular
atresia results in rapid depletion of germ cells from the cohort of the ovary. At the time of …

Increased oxidative stress (OS) due to in vitro culture conditions can affect the quality of
denuded eggs during various assisted reproductive technologies (ARTs). Presence of intact …

Cyclic nucleotide phosphodiesterases (PDEs) are group of enzymes that hydrolyze cyclic
nucleotides in wide variety of cell types including encircling granulosa cells as well as …

Simple Summary NOX4, PDE11A and GHR have previously been screened as candidate
genes for litter size in sheep. Therefore, it is necessary to validate these genes in the sheep …