Variants in the Kv7. 2 channel subunit encoded by the KCNQ2 gene cause epileptic
disorders ranging from a benign form with self‐limited epileptic seizures and normal …

Abstract Kv7. 1-Kv7. 5 (KCNQ1–5) K+ channels are voltage-gated K+ channels with major
roles in neurons, muscle cells and epithelia where they underlie physiologically important …

Ion channels activated around the subthreshold membrane potential determine the
likelihood of neuronal firing in response to synaptic inputs, a process described as intrinsic …

Methamphetamine (METH), an abused psychostimulant, impairs cognition through
prolonged or even single-dose exposure, but animal experiments have shown contradictory …

The central nervous system, information integration center of the body, is mainly composed
of neurons and glial cells. The neuron is one of the most basic and important structural and …

Cognitive dysfunction is a core symptom common in psychiatric disorders including
depression that is primarily managed by antidepressants lacking efficacy in improving …

Children who experienced moderate perinatal asphyxia (MPA) are at risk of developing long
lasting subtle cognitive and behavioral deficits, including learning disabilities and emotional …

Pain is a regular and unavoidable experience that dramatically impacts people's quality of
life. Current treatments are often inadequate, expensive or invasive, thus, despite advances …