An update on the effectiveness of probiotics in the prevention and treatment of cancer
V Sankarapandian, BA Venmathi Maran, RL Rajendran… - Life, 2022 - mdpi.com
Probiotics are living microbes that play a significant role in protecting the host in various
ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is …
ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is …
Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease
H Barmaki, A Nourazarian… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is characterized by the accumulation of misfolded amyloid-beta
and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps …
and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps …
Autophagy-amplifying nanoparticles evoke immunogenic cell death combined with anti-PD-1/PD-L1 for residual tumors immunotherapy after RFA
S Zhang, Y Huang, S Pi, H Chen, F Ye, C Wu… - Journal of …, 2023 - Springer
Incomplete radiofrequency ablation (IRFA) triggers mild protective autophagy in residual
tumor cells and results in an immunosuppressive microenvironment. This accelerates the …
tumor cells and results in an immunosuppressive microenvironment. This accelerates the …
Complex roles of autophagy in cancer development, immune evasion, and drug resistance
X Niu, Q You, K Hou, Y Tian, P Wei, Y Zhu, B Gao… - Drug Resistance …, 2024 - Elsevier
Macroautophagy/autophagy is a highly conserved evolutionary mechanism that involves
lysosomes for the degradation of cytoplasmic components including organelles. The …
lysosomes for the degradation of cytoplasmic components including organelles. The …
Novel effects of statins on cancer via autophagy
D Mengual, LE Medrano, W Villamizar-Villamizar… - Pharmaceuticals, 2022 - mdpi.com
Cancer is one of the main causes of death globally. Most of the molecular mechanisms
underlying cancer are marked by complex aberrations that activate the critical cell-signaling …
underlying cancer are marked by complex aberrations that activate the critical cell-signaling …
Molecular mechanisms of chloroquine and hydroxychloroquine used in cancer therapy
JB De Sanctis, J Charris, Z Blanco… - Anti-Cancer Agents …, 2023 - benthamdirect.com
Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …
Overexpression of TP53INP2 promotes apoptosis in clear cell renal cell cancer via Caspase‐8/TRAF6 signaling pathway
X Li, D Hu, Y Li, Y Luo, B Liang, K Yu… - Journal of …, 2022 - Wiley Online Library
Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape
apoptosis. The tumor protein p53‐inducible nuclear protein 2 (TP53INP2), known as an …
apoptosis. The tumor protein p53‐inducible nuclear protein 2 (TP53INP2), known as an …
Autophagy inhibition suppresses hormone production and cell growth in pituitary tumor cells: A potential approach to pituitary tumors
M Satou, J Wang, T Nakano-Tateno… - Molecular and Cellular …, 2024 - Elsevier
Pituitary tumors (PTs) represent about 10% of all intracranial tumors, and most are benign.
However, some PTs exhibit continued growth despite multimodal therapies. Although …
However, some PTs exhibit continued growth despite multimodal therapies. Although …
Drug repositioning identifies potential autophagy inhibitors for the LIR motif p62/SQSTM1 protein
Autophagy is a critical cellular process for degrading damaged organelles and proteins
under stressful conditions and has casually been shown to contribute to tumor survival and …
under stressful conditions and has casually been shown to contribute to tumor survival and …
The role of LncRNA-mediated autophagy in cancer progression
Z Liu, J Tang, M Yang, Z Yang, J Xia - Frontiers in Cell and …, 2024 - frontiersin.org
Long non-coding RNAs (lncRNAs) are a sort of transcripts that are more than 200
nucleotides in length. In recent years, many studies have revealed the modulatory role of …
nucleotides in length. In recent years, many studies have revealed the modulatory role of …