Potential Benefits of Black Chokeberry (Aronia melanocarpa) Fruits and Their Constituents in Improving Human Health

Y Ren, T Frank, G Meyer, J Lei, JR Grebenc… - Molecules, 2022 - mdpi.com
Aronia berry (black chokeberry) is a shrub native to North America, of which the fresh fruits
are used in the food industry to produce different types of dietary products. The fruits of …

Golgi-targeting anticancer natural products

MN Khine, K Sakurai - Cancers, 2023 - mdpi.com
Simple Summary A selected set of natural products that target the structure and function of
the Golgi apparatus in cancer cells is highlighted in this review. The potential for modulating …

Embellicines CE: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.

ZY Al Subeh, L Flores-Bocanegra… - Journal of Natural …, 2023 - ACS Publications
Macrocyclic alkaloids with a cyclopenta [b] fluorene ring system are a relatively young
structural class of fungal metabolites, with the first members reported in 2013. Bioassay …

The Cytotoxic Cardiac Glycoside (−)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets

Y Ren, EN Kaweesa, L Tian, S Wu… - Journal of Natural …, 2023 - ACS Publications
A cardiac glycoside epoxide,(−)-cryptanoside A (1), was isolated from the stems of
Cryptolepis dubia collected in Laos, for which the complete structure was confirmed by …

Discovery of Michael reaction acceptors from the leaves of Ailanthus altissima by a modified tactic

ZK Duan, SS Guo, L Ye, ZH Gao, D Liu, GD Yao… - Phytochemistry, 2023 - Elsevier
Structural characteristics-guided investigation of Ailanthus altissima (Mill.) Swingle resulted
in the isolation and identification of seven undescribed potential Michael reaction acceptors …

Development of Potential Therapeutic Agents from Black Elderberries (the Fruits of Sambucus nigra L.)

Y Ren, G Meyer, AT Anderson, KM Lauber, JC Gallucci… - Molecules, 2024 - mdpi.com
Elderberry (Sambucus nigra L.) is a widespread deciduous shrub, of which the fruits
(elderberries) are used in the food industry to produce different types of dietary supplement …

Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models

EN Kaweesa, JM Bazioli, HC Pierre… - Molecular …, 2023 - ACS Publications
Verticillins are epipolythiodioxopiperazine alkaloids isolated from a fungus with nanomolar
anti-tumor activity in high-grade serous ovarian cancer (HGSOC). HGSOC is the fifth leading …

Abietane diterpenoids and iridoids from Caryopteris mongolica

S Zhang, MAO Xudong, XU Hongtao… - Chinese Journal of …, 2023 - Elsevier
Abstract Six new abietane diterpenoids (1− 6) and five undescribed iridoids (7− 11) have
been isolated from the aerial parts of Caryopteris mongolica. The intricate structural …

Cytotoxicity of carvotacetones from Sphaeranthus africanus against cancer cells and their potential to induce apoptosis

HT Tran, N Kretschmer, L Huynh, R Bauer - Planta Medica, 2023 - thieme-connect.com
Three carvotacetones (1–3) isolated from Sphaeranthus africanus were screened in 60
cancer cell lines at the National Cancer Institute (NCI) within the Developmental …

Natural Products Dereplication: Databases and Analytical Methods

I Pérez-Victoria - Progress in the Chemistry of Organic Natural Products …, 2024 - Springer
The development of efficient methods for dereplication has been critical in the re-emergence
of the research in natural products as a source of drug leads. Current dereplication …