Virtual screening and biological evaluation of potential PD-1/PD-L1 immune checkpoint inhibitors as anti-hepatocellular carcinoma agents
MA Kamal, HA Badary, D Omran, HI Shousha… - ACS …, 2023 - ACS Publications
Blockade of the programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1)
immune checkpoint pathway is an efficient immunotherapeutic modality that provided …
immune checkpoint pathway is an efficient immunotherapeutic modality that provided …
Synthesis, structural determination, in vitro antioxidant and antibacterial efficacy of dispirooxindolopyrrolidine embedded indole heterocycle
N Arumugam, AI Almansour, MF Alkaltham… - Journal of Molecular …, 2024 - Elsevier
Synthesis of dispirooxindolopyrrolidine embedded indole hybrid heterocycle was achieved
in excellent yield employing intermolecular 1, 3-dipolar cycloaddition cascade reaction …
in excellent yield employing intermolecular 1, 3-dipolar cycloaddition cascade reaction …
[HTML][HTML] Asymmetric synthesis of enantiopure tetracyclic dispirooxindolopyrrolidine-piperidones via microwave-assisted multicomponent reaction: crystallographic …
H Jelizi, A Toumi, FIA Abdella, I Daoud… - Journal of Molecular …, 2024 - Elsevier
In an attempt towards the development of new antimicrobials, we synthesized by microwave-
assisted multicomponent reaction (MCR) of enantiopure (E, E)-3, 5-bisarylidene-N-[(S)-(-) …
assisted multicomponent reaction (MCR) of enantiopure (E, E)-3, 5-bisarylidene-N-[(S)-(-) …
Chemoselective and diastereodivergent synthesis of new spirooxindolo-pyrrolizidines and pyrrolidines stemming from unsymmetrical 1, 3-bis (arylidene) tetral-2-ones …
H Gazzeh, F Rouatbi, S Chniti, M Askri… - New Journal of …, 2022 - pubs.rsc.org
A theoretical and experimental study of a three-component one-pot cycloaddition reaction
involving unstabilized azomethine ylides and unsymmetrical exocyclic dienones featuring a …
involving unstabilized azomethine ylides and unsymmetrical exocyclic dienones featuring a …
Hydroazidation of phenacylideneoxindoles: Synthesis of 3-substituted 3-azido-1, 3-dihydro-2H-indol-2-ones via anti-electron addition
A Aisikaer, J Ma, J Li, X Li - Tetrahedron Letters, 2023 - Elsevier
A simple synthetic strategy of 3-substituted 3-azido-1, 3-dihydro-2H-indol-2-ones was
realized through hydroazidation of phenacylideneoxindoles with azidotrimethylsilane under …
realized through hydroazidation of phenacylideneoxindoles with azidotrimethylsilane under …