Network pharmacology approach for medicinal plants: review and assessment

F Noor, M Tahir ul Qamar, UA Ashfaq, A Albutti… - Pharmaceuticals, 2022 - mdpi.com
Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

Chlamydia trachomatis as a Current Health Problem: Challenges and Opportunities

R Rodrigues, C Sousa, N Vale - Diagnostics, 2022 - mdpi.com
Chlamydia is one of the most common sexually transmitted bacterial infections (STIs)
worldwide. It is caused by Chlamydia trachomatis (CT), which is an obligate intracellular …

Integrating Network Pharmacology and Molecular Docking Approaches to Decipher the Multi-Target Pharmacological Mechanism of Abrus precatorius L. Acting on …

F Noor, A Rehman, UA Ashfaq, MH Saleem, MK Okla… - Pharmaceuticals, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a notable health care load that imposes a serious impact
on the quality of life of patients. The small amount of reported data and multiple spectra of …

Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …

[HTML][HTML] Network pharmacology based virtual screening of Flavonoids from Dodonea angustifolia and the molecular mechanism against inflammation

MA Alamri, MT ul Qamar - Saudi Pharmaceutical Journal, 2023 - Elsevier
Inflammation is a nonspecific immune response against injury caused by a harmful agent
that strives to restore tissue function and homeostasis. Dodonaea angustifolia Lf …

Therapeutic effects of Crataegus monogyna inhibitors against breast cancer

GM Basavarajappa, A Rehman… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is a silent killer disorder among women and a serious economic burden in
healthcare management. Every 19 s, a woman is diagnosed with breast cancer, and every …

Designing a multi-epitope vaccine against Chlamydia pneumoniae by integrating the core proteomics, subtractive proteomics and reverse vaccinology-based …

F Noor, S Ahmad, M Saleem, H Alshaya… - Computers in Biology …, 2022 - Elsevier
Chlamydia pneumoniae, a pneumonia causing specie belonging to chlamydia bacterium. C.
pneumonia is considered as a leading cause of pneumonia. Apart from that, C. pneumoniae …

[HTML][HTML] Genome-level therapeutic targets identification and chimeric Vaccine designing against the Blastomyces dermatitidis

S Mursaleen, A Sarfraz, M Shehroz, A Zaman… - Heliyon, 2024 - cell.com
Blastomyces dermatitidis is a thermally dimorphic fungus that can cause serious and
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …

Design of multi-epitope based vaccine against Mycobacterium tuberculosis: a subtractive proteomics and reverse vaccinology based immunoinformatics approach

SS Nayak, G Sethi, K Ramadas - Journal of Biomolecular Structure …, 2023 - Taylor & Francis
Tuberculosis is an airborne transmissible disease caused by Mycobacterium tuberculosis
that infects millions of lives worldwide. There is still no single comprehensive therapy or …

Development of a Candidate Multi-Epitope Subunit Vaccine against Klebsiella aerogenes: Subtractive Proteomics and Immuno-Informatics Approach

A Umar, A Haque, YS Alghamdi, MM Mashraqi… - Vaccines, 2021 - mdpi.com
Klebsiella aerogenes is a Gram-negative bacterium which has gained considerable
importance in recent years. It is involved in 10% of nosocomial and community-acquired …