From therapeutic drug monitoring to model‐informed precision dosing for antibiotics
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
evolved as important tools to inform rational dosing of antibiotics in individual patients with …
Drug‐resistant tuberculosis: an update on disease burden, diagnosis and treatment
The emergence of antimicrobial resistance against Mycobacterium tuberculosis, the leading
cause of mortality due to a single microbial pathogen worldwide, represents a growing threat …
cause of mortality due to a single microbial pathogen worldwide, represents a growing threat …
Therapeutic drug monitoring in the treatment of tuberculosis: an update
A Alsultan, CA Peloquin - Drugs, 2014 - Springer
Tuberculosis (TB) is the world's second leading infectious killer. Cases of multidrug-resistant
(MDR-TB) and extremely drug-resistant (XDR-TB) have increased globally. Therapeutic …
(MDR-TB) and extremely drug-resistant (XDR-TB) have increased globally. Therapeutic …
Therapeutic drug monitoring by dried blood spot: progress to date and future directions
AJ Wilhelm, JCG den Burger, EL Swart - Clinical pharmacokinetics, 2014 - Springer
This article discusses dried blood spot (DBS) sampling in therapeutic drug monitoring
(TDM). The most important advantages of DBS sampling in TDM are the minimally invasive …
(TDM). The most important advantages of DBS sampling in TDM are the minimally invasive …
Emerging trends in paper spray mass spectrometry: Microsampling, storage, direct analysis, and applications
Recent advancements in the sensitivity of chemical instrumentation have led to increased
interest in the use of microsamples for translational and biomedical research. Paper …
interest in the use of microsamples for translational and biomedical research. Paper …
Dried blood spots analysis with mass spectrometry: potentials and pitfalls in therapeutic drug monitoring
MV Antunes, MF Charão, R Linden - Clinical biochemistry, 2016 - Elsevier
Therapeutic drug monitoring (TDM) relays in the availability of specialized laboratory
assays, usually available in reference centers that are not accessible to all patients. In this …
assays, usually available in reference centers that are not accessible to all patients. In this …
[HTML][HTML] Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges
G Günther - Clinical medicine, 2014 - Elsevier
Multidrug-resistant and extensively drug-resistant tuberculosis are recent global health
issues, which makes tuberculosis–after the success of short course treatment during the …
issues, which makes tuberculosis–after the success of short course treatment during the …
How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?
G Wong, FB Sime, J Lipman, JA Roberts - BMC infectious diseases, 2014 - Springer
High mortality and morbidity rates associated with severe infections in the critically ill
continue to be a significant issue for the healthcare system. In view of the diverse and …
continue to be a significant issue for the healthcare system. In view of the diverse and …
Linezolid-based regimens for multidrug-resistant tuberculosis (TB): a systematic review to establish or revise the current recommended dose for TB treatment
MS Bolhuis, OW Akkerman… - Clinical Infectious …, 2018 - academic.oup.com
Linezolid has been successfully used for treatment of multidrug-resistant tuberculosis (MDR-
TB). However, dose-and duration-related toxicity limit its use. Here, our aim was to search …
TB). However, dose-and duration-related toxicity limit its use. Here, our aim was to search …
Expert consensus statement on therapeutic drug monitoring and individualization of linezolid
B Lin, Y Hu, P Xu, T Xu, C Chen, L He, M Zhou… - Frontiers in Public …, 2022 - frontiersin.org
Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and
individualized treatment have been challenged since its approval. With the in-depth clinical …
individualized treatment have been challenged since its approval. With the in-depth clinical …