Hyperhomocysteinaemia has been regarded as a new modifiable risk factor for
atherosclerosis and vascular disease. Homocysteine is a branch‐point intermediate of …

The classic neurological and psychiatric features associated with vitamin B12 deficiency
have been well described and are the subject of many excellent review articles. The advent …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Background: The standard screening test for vitamin B12 deficiency, measurement of total
plasma vitamin B12, has limitations of sensitivity and specificity. Plasma vitamin B12 bound …

Cellular uptake of cobalamin is facilitated by a receptor-mediated endocytosis process
involving transcobalamin, a plasma protein that binds cobalamin and a cell surface receptor …

The pathogenesis of human spontaneous abortion involves a complex interaction of several
genetic and environmental factors. The firm association between increased homocysteine …

Abstract A common polymorphism (775G> C) in the vitamin B12 transport protein,
transcobalamin II (TCII), has been identified in which proline replaces arginine at codon 259 …

One-carbon metabolism is under the influence of folate, vitamin B12 and genetic
polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C→ T and 1298 A→ …

Thoroughly revised and updated, Handbook of Vitamins highlights the recent research in
vitamins and gene expression, vitamin-dependent genes, and vitamin effect on DNA …

Hyperhomocysteinemia (Hhcy) is an established risk factor for various pathologies including
arterial vascular disease and venous thrombosis, congenital malformations and other …