Selection against admixture and gene regulatory divergence in a long-term primate field study

TP Vilgalys, AS Fogel, JA Anderson, RS Mututua… - Science, 2022 - science.org
Genetic admixture is central to primate evolution. We combined 50 years of field
observations of immigration and group demography with genomic data from~ 9 generations …

The Bioinformatic Applications of Hi-C and Linked Reads

L Jiang, MA Quail, J Fraser-Govil… - Genomics …, 2024 - academic.oup.com
Long-range sequencing grants insight into additional genetic information beyond what can
be accessed by both short reads and modern long-read technology. Several new …

Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas

KL Chiou, MC Janiak, IA Schneider-Crease… - Nature ecology & …, 2022 - nature.com
Primates have adapted to numerous environments and lifestyles but very few species are
native to high elevations. Here we investigated high-altitude adaptations in the gelada …

Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons

JA Anderson, AJ Lea, TN Voyles… - … of the Royal …, 2022 - royalsocietypublishing.org
The social environment is a major determinant of morbidity, mortality and Darwinian fitness
in social animals. Recent studies have begun to uncover the molecular processes …

Gelada genomes highlight events of gene flow, hybridisation and local adaptation that track past climatic changes

M Caldon, G Mutti, A Mondanaro, H Imai… - Molecular …, 2024 - Wiley Online Library
Theropithecus gelada, the last surviving species of this genus, occupy a unique and highly
specialised ecological niche in the Ethiopian highlands. A subdivision into three …

Assessing the recovery of Y chromosome microsatellites with population genomic data using Papio and Theropithecus genomes

G Mutti, G Oteo-Garcia, M Caldon, MJF da Silva… - Scientific Reports, 2023 - nature.com
Y chromosome markers can shed light on male-specific population dynamics but for many
species no such markers have been discovered and are available yet, despite the potential …

[HTML][HTML] 3D genome organization and its study in livestock breeding

J Cheng, X Cao, S Wang, J Zhang, B Yue… - Journal of Integrative …, 2024 - Elsevier
Eukaryotic genomes are hierarchically packaged into cell nucleus, affecting gene regulation.
The genome is organized into multiscale structural units, including chromosome territories …

DNA methylation signatures of early-life adversity are exposure-dependent in wild baboons

JA Anderson, D Lin, AJ Lea… - Proceedings of the …, 2024 - National Acad Sciences
The early-life environment can profoundly shape the trajectory of an animal's life, even years
or decades later. One mechanism proposed to contribute to these early-life effects is DNA …

Human herpesvirus diversity is altered in HLA class I binding peptides

WH Palmer, M Telford, A Navarro… - Proceedings of the …, 2022 - National Acad Sciences
Herpesviruses are ubiquitous, genetically diverse DNA viruses, with long-term presence in
humans associated with infrequent but significant pathology. Human leukocyte antigen …

[HTML][HTML] Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons

W Lin, JD Wall, G Li, D Newman, Y Yang, M Abney… - Cell Genomics, 2024 - cell.com
Steady-state expression quantitative trait loci (eQTLs) explain only a fraction of disease-
associated loci identified through genome-wide association studies (GWASs), while eQTLs …