Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …

Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …

Alzheimer's disease (AD) is a progressive multifactorial neurodegenerative disorder.
Currently, no effective treatment is available and this is due to multiple factors involved in …

In our endeavor towards the development of potent multitarget ligands for the treatment of
Alzheimer's disease, a series of triazine-triazolopyrimidine hybrids were designed …

Two series of (nicotinonitrile-thiazole)-based Schiff bases 1 and their bis (Schiff bases)
analogs 2 are efficiently prepared in this study. A one-pot protocol was designed to prepare …

Zaleya pentandra L. jaffery is the only species of the genus Zaleya that grows in the
Cholistan desert, Pakistan. It is a Xero-halophyte plant with high phenolic and flavonoid …

Majority of the representative drugs customarily interact with multiple targets manifesting
unintended side effects. In addition, drug resistance and over expression of the cellular …

Abstract Pyridine‐2 (1H)‐thiones were used to prepare two novel series of nicotinonitriles
and thieno [2, 3‐b] pyridines using piperazine as an eco‐friendly catalyst and under …

A series of hybrids of benzimidazole and 1, 3, 5-triazine were designed and synthesized and
evaluated as multi-target agents for the treatment of Alzheimer's disease. 24 compounds …