Review of methods for intraoperative margin detection for breast conserving surgery

BW Maloney, DM McClatchy, BW Pogue… - … of biomedical optics, 2018 - spiedigitallibrary.org
Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as
the margins of the resected tissue are free of disease according to consensus guidelines for …

Lobular breast carcinoma and its variants

EA Rakha, IO Ellis - Seminars in diagnostic pathology, 2010 - Elsevier
Lobular carcinoma is a special type of breast cancer that shows distinct clinical presentation,
morphologic and molecular features, and clinical behavior, and its incidence is rising in …

Are mastectomies on the rise? A 13-year trend analysis of the selection of mastectomy versus breast conservation therapy in 5865 patients

KP McGuire, AA Santillan, P Kaur, T Meade… - Annals of surgical …, 2009 - Springer
Background The equivalency of survival between mastectomy and breast conservation
therapy (BCT) has long been established, resulting in two decades of predominant BCT …

Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial

NMA Krekel, MH Haloua, AMFL Cardozo… - The lancet …, 2013 - thelancet.com
Background Breast-conserving surgery for palpable breast cancer is associated with tumour-
involved margins in up to 41% of cases and excessively large excision volumes. Ultrasound …

Adipose-derived Mesenchymal Stem Cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling

V Eterno, A Zambelli, L Pavesi, L Villani, V Zanini… - …, 2013 - pmc.ncbi.nlm.nih.gov
Adipose tissue is a reservoir of Mesenchymal Stem Cells (Adipose-derived Mesenchymal
Stem Cells, ASCs), endowed with regenerative properties. Fat graft was proposed for breast …

Predictors of surgical margin status in breast-conserving surgery within a breast screening program

ED Kurniawan, MH Wong, I Windle, A Rose… - Annals of Surgical …, 2008 - Springer
Background Breast-conserving surgery (BCS) requires clear surgical margins to minimize
local recurrence. We sought to identify groups of patients at higher risk of involved margins …

The role of reexcision for positive margins in optimizing local disease control after breast‐conserving surgery for cancer

D Aziz, E Rawlinson, SA Narod, P Sun… - The breast …, 2006 - Wiley Online Library
One of the most important factors associated with local recurrence after lumpectomy in
breast cancer patients is the status of the surgical margin. Standard surgical practice is to …

Intraoperative margin assessment and re-excision rate in breast conserving surgery

FJ Fleming, ADK Hill, EW Mc Dermott… - European Journal of …, 2004 - Elsevier
Aim: The aim of this study was to assess the efficacy of intraoperative margin assessment in
obtaining clear margins in conserving surgery for breast cancer. Methods: Two hundred and …

Oncological advantages of oncoplastic breast‐conserving surgery in treatment of early breast cancer

SK Down, PK Jha, MBBS MS MSc, A Burger… - The breast …, 2013 - Wiley Online Library
The standard approach to breast‐conserving surgery is wide local excision of the tumor and
radiotherapy. However, a significant number of patients require further surgery to obtain …

Intraoperative ultrasound is associated with clear lumpectomy margins for palpable infiltrating ductal breast cancer

MM Moore, LA Whitney, L Cerilli, JZ Imbrie… - Annals of …, 2001 - journals.lww.com
Objective To evaluate the efficacy of intraoperative ultrasound in obtaining adequate
surgical margins in women undergoing lumpectomy for palpable breast cancer. Summary …