The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic continues to pose a major
public health threat especially in countries with low vaccination rates. To better understand …

A recent report found that rare predicted loss-of-function (pLOF) variants across 13
candidate genes in TLR3-and IRF7-dependent type I IFN pathways explain up to 3.5% of …

COVID-19 has caused the recent pandemic of respiratory infection, which threatened global
health. The severity of the symptoms varies among affected individuals, from asymptotic or …

Genome-wide association studies (GWASs) examine the association between genotype and
phenotype while adjusting for a set of covariates. Although the covariates may have non …

While there is undeniable evidence to link endosomal acid‐base homeostasis to viral
pathogenesis, the lack of druggable molecular targets has hindered translation from bench …

Abstract Coronavirus 2019 (COVID-19) is a viral disease caused by severe acute respiratory
syndrome coronavirus-2 (SARS CoV-2). The disease resulted in global morbidity and …

Hoping to find genomic clues linked to COVID-19 and end the pandemic has driven
scientists' tremendous efforts to try all kinds of research. Signs of progress have been …

COVID-19 vaccines can be the tugboats for preventing SARS-CoV-2 infections when they
are practical and, more importantly, without adverse effects. However, the reality is that they …

Genes functionally associated with SARS-CoV-2 infection and genes functionally related to
the COVID-19 disease can be different, whose distinction will become the first essential step …